All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 10:11 AM ET.
| Rank | Player | Match |
| 1 | Cooper Kupp | LAR vs Dal |
| 2 | Davante Adams | LV @ KC |
| 3 | Stefon Diggs | Buf vs Pit |
| 4 | Justin Jefferson | Min vs Chi |
| 5 | Derrick Henry | Ten @ Wsh |
| 6 | Christian McCaffrey | Car vs SF |
| 7 | Austin Ekeler | LAC @ Cle |
| 8 | Travis Kelce | KC vs LV |
| 9 | Nick Chubb | Cle vs LAC |
| 10 | Deebo Samuel | SF @ Car |
| 11 | Dalvin Cook | Min vs Chi |
| 12 | Tyreek Hill (GTD) | Mia @ NYJ |
| 13 | Ja'Marr Chase | Cin @ Bal |
| 14 | Leonard Fournette | TB vs Atl |
| 15 | Mike Evans | TB vs Atl |
| 16 | Joe Mixon | Cin @ Bal |
| 17 | A.J. Brown | Phi @ Ari |
| 18 | Alvin Kamara (GTD) | NO vs Sea |
| 19 | Mark Andrews | Bal vs Cin |
| 20 | Josh Jacobs | LV @ KC |
| 21 | Tee Higgins (GTD) | Cin @ Bal |
| 22 | Christian Kirk | Jax vs Hou |
| 23 | Jaylen Waddle (GTD) | Mia @ NYJ |
| 24 | Jamaal Williams | Det @ NE |
| 25 | James Robinson | Jax vs Hou |
| 26 | Mike Williams | LAC @ Cle |
| 27 | Chris Olave | NO vs Sea |
| 28 | Miles Sanders | Phi @ Ari |
| 29 | Marquise Brown | Ari vs Phi |
| 30 | Amon-Ra St. Brown (GTD) | Det @ NE |
| 31 | CeeDee Lamb (GTD) | Dal @ LAR |
| 32 | Chris Godwin | TB vs Atl |
| 33 | J.K. Dobbins | Bal vs Cin |
| 34 | Dameon Pierce | Hou @ Jax |
| 35 | Breece Hall | NYJ vs Mia |
| Rank | Player | Match |
| 36 | Jeff Wilson | SF @ Car |
| 37 | Damien Harris | NE vs Det |
| 38 | Brandin Cooks | Hou @ Jax |
| 39 | Clyde Edwards-Helaire | KC vs LV |
| 40 | D.K. Metcalf | Sea @ NO |
| 41 | Tyler Lockett | Sea @ NO |
| 42 | Najee Harris | Pit @ Buf |
| 43 | Drake London | Atl @ TB |
| 44 | James Conner | Ari vs Phi |
| 45 | Rhamondre Stevenson | NE vs Det |
| 46 | DeVonta Smith | Phi @ Ari |
| 47 | Amari Cooper | Cle vs LAC |
| 48 | Curtis Samuel | Wsh vs Ten |
| 49 | Rashaad Penny | Sea @ NO |
| 50 | Adam Thielen | Min vs Chi |
| 51 | Robert Woods | Ten @ Wsh |
| 52 | Devin Singletary | Buf vs Pit |
| 53 | Gabriel Davis | Buf vs Pit |
| 54 | Terry McLaurin | Wsh vs Ten |
| 55 | David Montgomery (GTD) | Chi @ Min |
| 56 | JuJu Smith-Schuster (GTD) | KC vs LV |
| 57 | Diontae Johnson | Pit @ Buf |
| 58 | T.J. Hockenson | Det @ NE |
| 59 | Darren Waller | LV @ KC |
| 60 | Kareem Hunt | Cle vs LAC |
| 61 | Ezekiel Elliott | Dal @ LAR |
| 62 | D.J. Moore | Car vs SF |
| 63 | Brandon Aiyuk | SF @ Car |
| 64 | Raheem Mostert | Mia @ NYJ |
| 65 | Josh Reynolds (GTD) | Det @ NE |
| 66 | Devin Duvernay | Bal vs Cin |
| 67 | Garrett Wilson | NYJ vs Mia |
| 68 | Dallas Goedert | Phi @ Ari |
| 69 | Travis Etienne | Jax vs Hou |
| 70 | Tyler Higbee | LAR vs Dal |
