All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 11:31 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Chi |
| 2 | Puka Nacua | LAR @ Atl |
| 3 | De'Von Achane | Mia vs TB |
| 4 | Jahmyr Gibbs | Det @ Min |
| 5 | Jonathan Taylor | Ind vs Jax |
| 6 | Ja'Marr Chase | Cin vs Ari |
| 7 | Bijan Robinson | Atl vs LAR |
| 8 | Jaxon Smith-Njigba | Sea @ Car |
| 9 | Chase Brown | Cin vs Ari |
| 10 | Ashton Jeanty | LV vs NYG |
| 11 | James Cook | Buf vs Phi |
| 12 | Trey McBride | Ari @ Cin |
| 13 | Saquon Barkley | Phi @ Buf |
| 14 | Travis Etienne | Jax @ Ind |
| 15 | Amon-Ra St. Brown | Det @ Min |
| 16 | CeeDee Lamb | Dal @ Wsh |
| 17 | Javonte Williams | Dal @ Wsh |
| 18 | George Pickens | Dal @ Wsh |
| 19 | Drake London | Atl vs LAR |
| 20 | Derrick Henry | Bal @ GB |
| 21 | Josh Jacobs | GB vs Bal |
| 22 | Kyren Williams | LAR @ Atl |
| 23 | Chris Olave | NO @ Ten |
| 24 | Bucky Irving | TB @ Mia |
| 25 | RJ Harvey | Den @ KC |
| 26 | Nico Collins | Hou @ LAC |
| 27 | Mike Evans | TB @ Mia |
| 28 | Breece Hall | NYJ vs NE |
| 29 | Tyrone Tracy Jr. | NYG @ LV |
| 30 | Omarion Hampton | LAC vs Hou |
| 31 | Tee Higgins | Cin vs Ari |
| 32 | Aaron Jones | Min vs Det |
| 33 | Rico Dowdle | Car vs Sea |
| 34 | Jaylen Warren (Q) | Pit @ Cle |
| 35 | Kenneth Walker III | Sea @ Car |
| Rank | Player | Match |
| 36 | A.J. Brown (Q) | Phi @ Buf |
| 37 | D'Andre Swift | Chi @ SF |
| 38 | Justin Jefferson | Min vs Det |
| 39 | Rhamondre Stevenson | NE @ NYJ |
| 40 | Terry McLaurin | Wsh vs Dal |
| 41 | Kenneth Gainwell | Pit @ Cle |
| 42 | Jauan Jennings | SF vs Chi |
| 43 | Jameson Williams | Det @ Min |
| 44 | Marvin Harrison Jr. | Ari @ Cin |
| 45 | Michael Carter | Ari @ Cin |
| 46 | Zay Flowers | Bal @ GB |
| 47 | Tetairoa McMillan | Car vs Sea |
| 48 | Stefon Diggs | NE @ NYJ |
| 49 | DJ Moore | Chi @ SF |
| 50 | Alvin Kamara | NO @ Ten |
| 51 | Michael Wilson | Ari @ Cin |
| 52 | Emeka Egbuka | TB @ Mia |
| 53 | Courtland Sutton | Den @ KC |
| 54 | Jakobi Meyers | Jax @ Ind |
| 55 | TreVeyon Henderson | NE @ NYJ |
| 56 | Tony Pollard | Ten vs NO |
| 57 | Jaylen Waddle | Mia vs TB |
| 58 | Alec Pierce | Ind vs Jax |
| 59 | Deebo Samuel | Wsh vs Dal |
| 60 | DeVonta Smith | Phi @ Buf |
| 61 | Kyle Pitts | Atl vs LAR |
| 62 | Wan'Dale Robinson | NYG @ LV |
| 63 | Juwan Johnson | NO @ Ten |
| 64 | Zach Charbonnet | Sea @ Car |
| 65 | Michael Pittman Jr. | Ind vs Jax |
| 66 | Hunter Henry | NE @ NYJ |
| 67 | Jake Ferguson | Dal @ Wsh |
| 68 | Ladd McConkey | LAC vs Hou |
| 69 | Brian Thomas Jr. | Jax @ Ind |
| 70 | George Kittle | SF vs Chi |
