All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 11:31 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Chi |
| 2 | De'Von Achane | Mia vs TB |
| 3 | Jahmyr Gibbs | Det @ Min |
| 4 | Jonathan Taylor | Ind vs Jax |
| 5 | Bijan Robinson | Atl vs LAR |
| 6 | Chase Brown | Cin vs Ari |
| 7 | Ashton Jeanty | LV vs NYG |
| 8 | James Cook | Buf vs Phi |
| 9 | Saquon Barkley | Phi @ Buf |
| 10 | Travis Etienne | Jax @ Ind |
| 11 | Javonte Williams | Dal @ Wsh |
| 12 | Derrick Henry | Bal @ GB |
| 13 | Josh Jacobs | GB vs Bal |
| 14 | Kyren Williams | LAR @ Atl |
| 15 | Bucky Irving | TB @ Mia |
| 16 | RJ Harvey | Den @ KC |
| 17 | Breece Hall | NYJ vs NE |
| 18 | Tyrone Tracy Jr. | NYG @ LV |
| 19 | Omarion Hampton | LAC vs Hou |
| 20 | Aaron Jones | Min vs Det |
| Rank | Player | Match |
| 21 | Rico Dowdle | Car vs Sea |
| 22 | Jaylen Warren (Q) | Pit @ Cle |
| 23 | Kenneth Walker III | Sea @ Car |
| 24 | D'Andre Swift | Chi @ SF |
| 25 | Rhamondre Stevenson | NE @ NYJ |
| 26 | Kenneth Gainwell | Pit @ Cle |
| 27 | Michael Carter | Ari @ Cin |
| 28 | Alvin Kamara | NO @ Ten |
| 29 | TreVeyon Henderson | NE @ NYJ |
| 30 | Tony Pollard | Ten vs NO |
| 31 | Zach Charbonnet | Sea @ Car |
| 32 | Kyle Monangai | Chi @ SF |
| 33 | Chris Rodriguez Jr. (Q) | Wsh vs Dal |
| 34 | David Montgomery | Det @ Min |
| 35 | Tyjae Spears | Ten vs NO |
| 36 | Raheim Sanders | Cle vs Pit |
| 37 | Woody Marks | Hou @ LAC |
| 38 | Blake Corum | LAR @ Atl |
| 39 | Chuba Hubbard | Car vs Sea |
| 40 | Dylan Sampson | Cle vs Pit |
