All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 11:24 AM ET.
| Rank | Player | Match |
| 1 | Jahmyr Gibbs | Det vs Min |
| 2 | Bijan Robinson | Atl @ TB |
| 3 | Jaxon Smith-Njigba | Sea vs Chi |
| 4 | Puka Nacua | LAR vs LAC |
| 5 | CeeDee Lamb | Dal vs Ari |
| 6 | Ja'Marr Chase | Cin vs Ten |
| 7 | Kenneth Walker III | KC @ Den |
| 8 | Derrick Henry | Bal @ Buf |
| 9 | Javonte Williams | Dal vs Ari |
| 10 | Kyren Williams | LAR vs LAC |
| 11 | Trey McBride | Ari @ Dal |
| 12 | James Cook | Buf vs Bal |
| 13 | Zay Flowers | Bal @ Buf |
| 14 | Chase Brown | Cin vs Ten |
| 15 | Bucky Irving | TB vs Atl |
| 16 | Tee Higgins | Cin vs Ten |
| 17 | Amon-Ra St. Brown | Det vs Min |
| 18 | Jonathan Taylor | Ind @ Jax |
| 19 | Jaylen Warren | Pit vs Cle |
| 20 | Drake London | Atl @ TB |
| 21 | Bhayshul Tuten | Jax vs Ind |
| 22 | George Pickens (Q) | Dal vs Ari |
| 23 | Ashton Jeanty | LV @ NYJ |
| 24 | Parker Washington | Jax vs Ind |
| 25 | Justin Jefferson | Min @ Det |
| 26 | Tony Pollard | Ten @ Cin |
| 27 | Brock Bowers | LV @ NYJ |
| 28 | Rhamondre Stevenson | NE @ Mia |
| 29 | D'Andre Swift | Chi @ Sea |
| 30 | Breece Hall (Q) | NYJ vs LV |
| 31 | Garrett Wilson | NYJ vs LV |
| 32 | Saquon Barkley | Phi @ Wsh |
| 33 | A.J. Brown (Q) | NE @ Mia |
| 34 | Michael Wilson | Ari @ Dal |
| 35 | Ollie Gordon | Mia vs NE |
| Rank | Player | Match |
| 36 | Quinshon Judkins | Cle @ Pit |
| 37 | Rachaad White | Wsh vs Phi |
| 38 | D.J. Moore (Q) | Buf vs Bal |
| 39 | Luther Burden III | Chi @ Sea |
| 40 | Jordan Mason | Min @ Det |
| 41 | Hunter Henry | NE @ Mia |
| 42 | D.K. Metcalf | Pit vs Cle |
| 43 | Rashee Rice | KC @ Den |
| 44 | Stefon Diggs | Wsh vs Phi |
| 45 | Omarion Hampton | LAC @ LAR |
| 46 | Colston Loveland (Q) | Chi @ Sea |
| 47 | Tre Tucker | LV @ NYJ |
| 48 | Jonah Coleman | Den vs KC |
| 49 | Trayveon Williams | Det vs Min |
| 50 | Braelon Allen | NYJ vs LV |
| 51 | Travis Kelce | KC @ Den |
| 52 | Germie Bernard | Pit vs Cle |
| 53 | Jaylen Waddle (Q) | Den vs KC |
| 54 | Zach Charbonnet (Q) | Sea vs Chi |
| 55 | Sam LaPorta | Det vs Min |
| 56 | Jeremiyah Love | Ari @ Dal |
| 57 | Brenton Strange | Jax vs Ind |
| 58 | Ladd McConkey | LAC @ LAR |
| 59 | Omar Cooper | NYJ vs LV |
| 60 | Tyler Warren | Ind @ Jax |
| 61 | Blake Corum | LAR vs LAC |
| 62 | Chris Godwin | TB vs Atl |
| 63 | Dalton Kincaid (Q) | Buf vs Bal |
| 64 | Malik Washington | Mia vs NE |
| 65 | Wan'Dale Robinson | Ten @ Cin |
| 66 | Jakobi Meyers (Q) | Jax vs Ind |
| 67 | KC Concepcion Jr. | Cle @ Pit |
| 68 | Khalil Shakir | Buf vs Bal |
| 69 | Demario Douglas | NE @ Mia |
| 70 | Rico Dowdle | Pit vs Cle |
