All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 11:54 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Ten |
| 2 | De'Von Achane | Mia @ Pit |
| 3 | Jahmyr Gibbs | Det @ LAR |
| 4 | Bijan Robinson | Atl @ TB |
| 5 | Derrick Henry | Bal @ Cin |
| 6 | Jonathan Taylor | Ind @ Sea |
| 7 | Saquon Barkley | Phi vs LV |
| 8 | James Cook | Buf @ NE |
| 9 | Chase Brown | Cin vs Bal |
| 10 | Josh Jacobs | GB @ Den |
| 11 | Javonte Williams | Dal vs Min |
| 12 | Woody Marks | Hou vs Ari |
| 13 | Ashton Jeanty | LV @ Phi |
| 14 | Rico Dowdle | Car @ NO |
| 15 | Breece Hall | NYJ @ Jax |
| 16 | Kyren Williams | LAR vs Det |
| 17 | Bucky Irving | TB vs Atl |
| 18 | Travis Etienne | Jax vs NYJ |
| 19 | Quinshon Judkins | Cle @ Chi |
| 20 | Jaylen Warren | Pit vs Mia |
| Rank | Player | Match |
| 21 | TreVeyon Henderson | NE vs Buf |
| 22 | Kenneth Walker III | Sea vs Ind |
| 23 | RJ Harvey | Den vs GB |
| 24 | Tyrone Tracy Jr. | NYG vs Wsh |
| 25 | D'Andre Swift | Chi vs Cle |
| 26 | Omarion Hampton | LAC @ KC |
| 27 | Devin Neal (Q) | NO vs Car |
| 28 | Kareem Hunt | KC vs LAC |
| 29 | Kenneth Gainwell | Pit vs Mia |
| 30 | David Montgomery | Det @ LAR |
| 31 | Tony Pollard | Ten @ SF |
| 32 | Zach Charbonnet | Sea vs Ind |
| 33 | Aaron Jones | Min @ Dal |
| 34 | Bam Knight | Ari @ Hou |
| 35 | Chuba Hubbard | Car @ NO |
| 36 | Chris Rodriguez Jr. (Q) | Wsh @ NYG |
| 37 | Kyle Monangai | Chi vs Cle |
| 38 | Devin Singletary | NYG vs Wsh |
| 39 | Tyjae Spears | Ten @ SF |
| 40 | Rhamondre Stevenson | NE vs Buf |
