All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 11:04 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF @ NYG |
| 2 | Jonathan Taylor | Ind @ Pit |
| 3 | Jahmyr Gibbs | Det vs Min |
| 4 | Bijan Robinson | Atl @ NE |
| 5 | De'Von Achane | Mia vs Bal |
| 6 | Jaxon Smith-Njigba | Sea @ Wsh |
| 7 | Puka Nacua | LAR vs NO |
| 8 | James Cook | Buf vs KC |
| 9 | Josh Jacobs | GB vs Car |
| 10 | Ja'Marr Chase | Cin vs Chi |
| 11 | Kyren Williams | LAR vs NO |
| 12 | Amon-Ra St. Brown | Det vs Min |
| 13 | Derrick Henry | Bal @ Mia |
| 14 | D'Andre Swift (Q) | Chi @ Cin |
| 15 | CeeDee Lamb | Dal vs Ari |
| 16 | Zay Flowers | Bal @ Mia |
| 17 | Javonte Williams | Dal vs Ari |
| 18 | Trey McBride | Ari @ Dal |
| 19 | Justin Jefferson | Min @ Det |
| 20 | Ashton Jeanty | LV vs Jax |
| 21 | Travis Etienne | Jax @ LV |
| 22 | Rashee Rice | KC @ Buf |
| 23 | Davante Adams | LAR vs NO |
| 24 | Jaylen Waddle | Mia vs Bal |
| 25 | Chase Brown | Cin vs Chi |
| 26 | Rome Odunze | Chi @ Cin |
| 27 | Marvin Harrison Jr. | Ari @ Dal |
| 28 | Jaylen Warren | Pit vs Ind |
| 29 | Tucker Kraft | GB vs Car |
| 30 | George Pickens | Dal vs Ari |
| 31 | Ladd McConkey | LAC @ Ten |
| 32 | Kimani Vidal | LAC @ Ten |
| 33 | D.K. Metcalf | Pit vs Ind |
| 34 | Keenan Allen | LAC @ Ten |
| 35 | Tyler Warren | Ind @ Pit |
| Rank | Player | Match |
| 36 | Michael Pittman Jr. | Ind @ Pit |
| 37 | Nico Collins | Hou vs Den |
| 38 | Alvin Kamara | NO @ LAR |
| 39 | Drake London | Atl @ NE |
| 40 | Brian Thomas Jr. | Jax @ LV |
| 41 | Kenneth Walker III | Sea @ Wsh |
| 42 | Tyrone Tracy Jr. | NYG vs SF |
| 43 | Deebo Samuel | Wsh vs Sea |
| 44 | Quentin Johnston | LAC @ Ten |
| 45 | Bam Knight | Ari @ Dal |
| 46 | George Kittle | SF @ NYG |
| 47 | Tetairoa McMillan | Car @ GB |
| 48 | J.K. Dobbins | Den vs LV |
| 49 | Jacory Croskey-Merritt | Wsh vs Sea |
| 50 | Rhamondre Stevenson | NE vs Atl |
| 51 | Jordan Addison | Min @ Det |
| 52 | Chris Olave | NO @ LAR |
| 53 | Stefon Diggs | NE vs Atl |
| 54 | Woody Marks | Hou vs Den |
| 55 | Courtland Sutton | Den vs LV |
| 56 | Oronde Gadsden | LAC @ Ten |
| 57 | David Montgomery | Det vs Min |
| 58 | DJ Moore | Chi @ Cin |
| 59 | Romeo Doubs | GB vs Car |
| 60 | Kareem Hunt | KC @ Buf |
| 61 | Brock Bowers | LV vs Jax |
| 62 | Rico Dowdle | Car @ GB |
| 63 | Tee Higgins | Cin vs Chi |
| 64 | Travis Kelce | KC @ Buf |
| 65 | Xavier Worthy | KC @ Buf |
| 66 | Wan'Dale Robinson | NYG vs SF |
| 67 | Jameson Williams | Det vs Min |
| 68 | Sam LaPorta | Det vs Min |
| 69 | Khalil Shakir | Buf vs KC |
| 70 | Cooper Kupp | Sea @ Wsh |
