All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 8:53 AM ET.
| Rank | Player | Match |
| 1 | Saquon Barkley | Phi vs Cle |
| 2 | Derrick Henry | Bal vs Wsh |
| 3 | CeeDee Lamb | Dal vs Det |
| 4 | Ja'Marr Chase | Cin @ NYG |
| 5 | Alvin Kamara | NO vs TB |
| 6 | Bijan Robinson | Atl @ Car |
| 7 | Amon-Ra St. Brown | Det @ Dal |
| 8 | Jahmyr Gibbs | Det @ Dal |
| 9 | Chuba Hubbard | Car vs Atl |
| 10 | J.K. Dobbins | LAC @ Den |
| 11 | Breece Hall | NYJ vs Buf |
| 12 | Drake London | Atl @ Car |
| 13 | Jayden Reed | GB vs Ari |
| 14 | Josh Jacobs | GB vs Ari |
| 15 | A.J. Brown | Phi vs Cle |
| 16 | Stefon Diggs | Hou @ NE |
| 17 | James Conner | Ari @ GB |
| 18 | DJ Moore | Chi vs Jax |
| 19 | Mike Evans | TB @ NO |
| 20 | David Montgomery | Det @ Dal |
| 21 | Tony Pollard | Ten vs Ind |
| 22 | Chris Godwin | TB @ NO |
| 23 | Bucky Irving | TB @ NO |
| 24 | Joe Mixon (Q) | Hou @ NE |
| 25 | Tee Higgins | Cin @ NYG |
| 26 | D'Andre Swift | Chi vs Jax |
| 27 | Diontae Johnson (Q) | Car vs Atl |
| 28 | Garrett Wilson | NYJ vs Buf |
| 29 | DeVonta Smith | Phi vs Cle |
| 30 | Terry McLaurin | Wsh @ Bal |
| 31 | James Cook (Q) | Buf @ NYJ |
| 32 | Rico Dowdle | Dal vs Det |
| 33 | Najee Harris | Pit @ LV |
| 34 | Marvin Harrison Jr. | Ari @ GB |
| 35 | Zay Flowers | Bal vs Wsh |
| Rank | Player | Match |
| 36 | Wan'Dale Robinson | NYG vs Cin |
| 37 | Darnell Mooney | Atl @ Car |
| 38 | Brian Thomas Jr. | Jax @ Chi |
| 39 | Chris Olave | NO vs TB |
| 40 | Tank Dell | Hou @ NE |
| 41 | Chase Brown (Q) | Cin @ NYG |
| 42 | Javonte Williams | Den vs LAC |
| 43 | George Pickens | Pit @ LV |
| 44 | Travis Etienne Jr. | Jax @ Chi |
| 45 | Jameson Williams | Det @ Dal |
| 46 | Rashid Shaheed | NO vs TB |
| 47 | Jerome Ford | Cle @ Phi |
| 48 | Amari Cooper | Cle @ Phi |
| 49 | Zack Moss | Cin @ NYG |
| 50 | Brian Robinson Jr. (Q) | Wsh @ Bal |
| 51 | Christian Kirk | Jax @ Chi |
| 52 | Josh Downs (Q) | Ind @ Ten |
| 53 | Jakobi Meyers (Q) | LV vs Pit |
| 54 | Brock Bowers | LV vs Pit |
| 55 | Darius Slayton | NYG vs Cin |
| 56 | Devin Singletary (Q) | NYG vs Cin |
| 57 | Courtland Sutton | Den vs LAC |
| 58 | Jake Ferguson | Dal vs Det |
| 59 | Trey McBride | Ari @ GB |
| 60 | Antonio Gibson | NE vs Hou |
| 61 | Trey Sermon | Ind @ Ten |
| 62 | Ladd McConkey | LAC @ Den |
| 63 | Calvin Ridley | Ten vs Ind |
| 64 | Austin Ekeler | Wsh @ Bal |
| 65 | Tyjae Spears | Ten vs Ind |
| 66 | Sam LaPorta | Det @ Dal |
| 67 | Tucker Kraft | GB vs Ari |
| 68 | Dontayvion Wicks | GB vs Ari |
| 69 | Jalen Tolbert | Dal vs Det |
| 70 | Alexander Mattison | LV vs Pit |
