All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 8:52 AM ET.
| Rank | Player | Match |
| 1 | Saquon Barkley | Phi vs Cle |
| 2 | Derrick Henry | Bal vs Wsh |
| 3 | Alvin Kamara | NO vs TB |
| 4 | Bijan Robinson | Atl @ Car |
| 5 | Jahmyr Gibbs | Det @ Dal |
| 6 | Chuba Hubbard | Car vs Atl |
| 7 | J.K. Dobbins | LAC @ Den |
| 8 | Breece Hall | NYJ vs Buf |
| 9 | Josh Jacobs | GB vs Ari |
| 10 | James Conner | Ari @ GB |
| 11 | David Montgomery | Det @ Dal |
| 12 | Tony Pollard | Ten vs Ind |
| 13 | Bucky Irving | TB @ NO |
| 14 | Joe Mixon (Q) | Hou @ NE |
| 15 | D'Andre Swift | Chi vs Jax |
| 16 | James Cook (Q) | Buf @ NYJ |
| 17 | Rico Dowdle | Dal vs Det |
| 18 | Najee Harris | Pit @ LV |
| 19 | Chase Brown (Q) | Cin @ NYG |
| 20 | Javonte Williams | Den vs LAC |
| Rank | Player | Match |
| 21 | Travis Etienne Jr. | Jax @ Chi |
| 22 | Jerome Ford | Cle @ Phi |
| 23 | Zack Moss | Cin @ NYG |
| 24 | Brian Robinson Jr. (Q) | Wsh @ Bal |
| 25 | Devin Singletary (Q) | NYG vs Cin |
| 26 | Antonio Gibson | NE vs Hou |
| 27 | Trey Sermon | Ind @ Ten |
| 28 | Austin Ekeler | Wsh @ Bal |
| 29 | Tyjae Spears | Ten vs Ind |
| 30 | Alexander Mattison | LV vs Pit |
| 31 | Tank Bigsby | Jax @ Chi |
| 32 | Braelon Allen | NYJ vs Buf |
| 33 | Tyler Allgeier | Atl @ Car |
| 34 | Justice Hill | Bal vs Wsh |
| 35 | Tyrone Tracy Jr. | NYG vs Cin |
| 36 | Roschon Johnson | Chi vs Jax |
| 37 | Emanuel Wilson | GB vs Ari |
| 38 | Jaleel McLaughlin | Den vs LAC |
| 39 | Ezekiel Elliott | Dal vs Det |
| 40 | Tyler Goodson | Ind @ Ten |
