All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:26 AM ET.
| Rank | Player | Match |
| 1 | Jonathan Taylor | Ind @ Jax |
| 2 | Christian McCaffrey | Car @ NYG |
| 3 | Saquon Barkley | NYG vs Car |
| 4 | Derrick Henry | Ten @ Buf |
| 5 | Joe Mixon | Cin @ Dal |
| 6 | Dalvin Cook | Min @ Phi |
| 7 | D'Andre Swift (GTD) | Det vs Wsh |
| 8 | Nick Chubb | Cle vs NYJ |
| 9 | Javonte Williams | Den vs Hou |
| 10 | Aaron Jones | GB vs Chi |
| 11 | Leonard Fournette (GTD) | TB @ NO |
| 12 | Najee Harris | Pit vs NE |
| 13 | Darrell Henderson | LAR vs Atl |
| 14 | James Conner | Ari @ LV |
| 15 | Antonio Gibson | Wsh @ Det |
| 16 | Josh Jacobs | LV vs Ari |
| 17 | Cordarrelle Patterson | Atl @ LAR |
| 18 | David Montgomery | Chi @ GB |
| 19 | Chase Edmonds | Mia @ Bal |
| 20 | A.J. Dillon | GB vs Chi |
| Rank | Player | Match |
| 21 | Ezekiel Elliott | Dal vs Cin |
| 22 | Miles Sanders | Phi vs Min |
| 23 | Kareem Hunt | Cle vs NYJ |
| 24 | James Robinson | Jax vs Ind |
| 25 | Michael Carter | NYJ @ Cle |
| 26 | Jeff Wilson | SF vs Sea |
| 27 | Rashaad Penny | Sea @ SF |
| 28 | Melvin Gordon | Den vs Hou |
| 29 | Devin Singletary | Buf vs Ten |
| 30 | Damien Harris | NE @ Pit |
| 31 | Mark Ingram (GTD) | NO vs TB |
| 32 | Rhamondre Stevenson | NE @ Pit |
| 33 | Travis Etienne | Jax vs Ind |
| 34 | Rex Burkhead | Hou @ Den |
| 35 | J.K. Dobbins (GTD) | Bal vs Mia |
| 36 | Tony Pollard | Dal vs Cin |
| 37 | Alvin Kamara (GTD) | NO vs TB |
| 38 | Breece Hall | NYJ @ Cle |
| 39 | Dameon Pierce | Hou @ Den |
| 40 | Jamaal Williams | Det vs Wsh |
