All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 11:26 AM ET.
| Rank | Player | Match |
| 1 | Jahmyr Gibbs | Det vs NO |
| 2 | Bijan Robinson | Atl @ Pit |
| 3 | Jonathan Taylor | Ind vs Bal |
| 4 | De'Von Achane | Mia @ LV |
| 5 | Saquon Barkley | Phi vs Wsh |
| 6 | Derrick Henry | Bal @ Ind |
| 7 | Chase Brown | Cin vs TB |
| 8 | Omarion Hampton | LAC vs Ari |
| 9 | James Cook | Buf @ Hou |
| 10 | Javonte Williams | Dal @ NYG |
| 11 | Breece Hall | NYJ @ Ten |
| 12 | Travis Etienne | NO @ Det |
| 13 | Kenneth Walker III | KC vs Den |
| 14 | D'Andre Swift | Chi @ Car |
| 15 | Cam Skattebo | NYG vs Dal |
| 16 | Bucky Irving | TB @ Cin |
| 17 | Ashton Jeanty | LV vs Mia |
| 18 | David Montgomery | Hou vs Buf |
| 19 | Bhayshul Tuten | Jax vs Cle |
| 20 | Jaylen Warren | Pit vs Atl |
| Rank | Player | Match |
| 21 | Rico Dowdle | Pit vs Atl |
| 22 | Jeremiyah Love (Q) | Ari @ LAC |
| 23 | Tony Pollard | Ten vs NYJ |
| 24 | Quinshon Judkins | Cle @ Jax |
| 25 | Chuba Hubbard | Car vs Chi |
| 26 | RJ Harvey | Den @ KC |
| 27 | MarShawn Lloyd | GB @ Min |
| 28 | J.K. Dobbins | Den @ KC |
| 29 | Kenneth Gainwell | TB @ Cin |
| 30 | Aaron Jones | Min vs GB |
| 31 | Jordan Mason | Min vs GB |
| 32 | Jacory Croskey-Merritt | Wsh @ Phi |
| 33 | Kyle Monangai | Chi @ Car |
| 34 | Rachaad White | Wsh @ Phi |
| 35 | Tyjae Spears | Ten vs NYJ |
| 36 | Jonathon Brooks | Car vs Chi |
| 37 | Woody Marks | Hou vs Buf |
| 38 | Chris Rodriguez Jr. | Jax vs Cle |
| 39 | Tyler Allgeier | Ari @ LAC |
| 40 | Mike Washington | LV vs Mia |
