All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:17 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF @ Ind |
| 2 | De'Von Achane | Mia vs Cin |
| 3 | Bijan Robinson | Atl @ Ari |
| 4 | Jahmyr Gibbs | Det vs Pit |
| 5 | Jonathan Taylor | Ind vs SF |
| 6 | Ja'Marr Chase | Cin @ Mia |
| 7 | Amon-Ra St. Brown | Det vs Pit |
| 8 | James Cook | Buf @ Cle |
| 9 | Trey McBride | Ari vs Atl |
| 10 | Derrick Henry | Bal vs NE |
| 11 | Chase Brown | Cin @ Mia |
| 12 | Nico Collins | Hou vs LV |
| 13 | CeeDee Lamb | Dal vs LAC |
| 14 | Jameson Williams | Det vs Pit |
| 15 | Chris Olave | NO vs NYJ |
| 16 | Drake London | Atl @ Ari |
| 17 | George Kittle | SF @ Ind |
| 18 | Javonte Williams | Dal vs LAC |
| 19 | Bucky Irving | TB @ Car |
| 20 | George Pickens | Dal vs LAC |
| 21 | Travis Etienne | Jax @ Den |
| 22 | Quinshon Judkins | Cle vs Buf |
| 23 | Rico Dowdle | Car vs TB |
| 24 | Mike Evans | TB @ Car |
| 25 | Michael Wilson | Ari vs Atl |
| 26 | Ashton Jeanty | LV @ Hou |
| 27 | Breece Hall | NYJ @ NO |
| 28 | Zay Flowers | Bal vs NE |
| 29 | TreVeyon Henderson | NE @ Bal |
| 30 | Omarion Hampton | LAC @ Dal |
| 31 | Tetairoa McMillan | Car vs TB |
| 32 | Justin Jefferson | Min @ NYG |
| 33 | D.K. Metcalf | Pit @ Det |
| 34 | Jaylen Warren | Pit @ Det |
| 35 | Brock Bowers | LV @ Hou |
| Rank | Player | Match |
| 36 | RJ Harvey | Den vs Jax |
| 37 | Aaron Jones | Min @ NYG |
| 38 | Ladd McConkey | LAC @ Dal |
| 39 | Emeka Egbuka | TB @ Car |
| 40 | Wan'Dale Robinson | NYG vs Min |
| 41 | Tyrone Tracy Jr. | NYG vs Min |
| 42 | Michael Carter | Ari vs Atl |
| 43 | Jaylen Waddle | Mia vs Cin |
| 44 | Jauan Jennings | SF @ Ind |
| 45 | Courtland Sutton | Den vs Jax |
| 46 | Juwan Johnson | NO vs NYJ |
| 47 | Kenneth Gainwell | Pit @ Det |
| 48 | Kyle Pitts | Atl @ Ari |
| 49 | David Montgomery | Det vs Pit |
| 50 | Tony Pollard | Ten vs KC |
| 51 | Stefon Diggs | NE @ Bal |
| 52 | Travis Kelce | KC @ Ten |
| 53 | Jakobi Meyers | Jax @ Den |
| 54 | Harold Fannin Jr. | Cle vs Buf |
| 55 | Tee Higgins | Cin @ Mia |
| 56 | Kareem Hunt | KC @ Ten |
| 57 | Chuba Hubbard | Car vs TB |
| 58 | Jordan Addison | Min @ NYG |
| 59 | Kimani Vidal | LAC @ Dal |
| 60 | Brian Thomas Jr. | Jax @ Den |
| 61 | Jayden Higgins | Hou vs LV |
| 62 | Mark Andrews | Bal vs NE |
| 63 | Chris Godwin | TB @ Car |
| 64 | Xavier Worthy | KC @ Ten |
| 65 | Audric Estime | NO vs NYJ |
| 66 | Michael Pittman Jr. | Ind vs SF |
| 67 | Darren Waller | Mia vs Cin |
| 68 | Tyler Warren | Ind vs SF |
| 69 | Oronde Gadsden | LAC @ Dal |
| 70 | Hunter Henry | NE @ Bal |
