All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 8:08 AM ET.
| Rank | Player | Match |
| 1 | Jahmyr Gibbs | Det vs GB |
| 2 | Bijan Robinson | Atl vs SF |
| 3 | Christian McCaffrey | SF @ Atl |
| 4 | Kenneth Walker III | KC @ Sea |
| 5 | Kyren Williams | LAR @ LV |
| 6 | Jonathan Taylor | Ind @ Min |
| 7 | Chuba Hubbard | Car vs TB |
| 8 | Jaylen Warren | Pit @ NO |
| 9 | Javonte Williams | Dal @ Phi |
| 10 | Ashton Jeanty | LV vs LAR |
| 11 | Bucky Irving | TB @ Car |
| 12 | Saquon Barkley (Q) | Phi vs Dal |
| 13 | Woody Marks | Hou vs NYG |
| 14 | J.K. Dobbins | Den @ Ari |
| 15 | Quinshon Judkins | Cle @ Ten |
| 16 | Aaron Jones | Min vs Ind |
| 17 | Breece Hall (Q) | NYJ vs Mia |
| 18 | Tony Pollard | Ten vs Cle |
| 19 | Ollie Gordon | Mia @ NYJ |
| 20 | Jordan Mason | Min vs Ind |
| Rank | Player | Match |
| 21 | Emanuel Wilson | Sea vs KC |
| 22 | Alvin Kamara | NO vs Pit |
| 23 | Josh Jacobs | GB @ Det |
| 24 | RJ Harvey | Den @ Ari |
| 25 | Braelon Allen | NYJ vs Mia |
| 26 | Cam Skattebo | NYG @ Hou |
| 27 | Tyler Allgeier | Ari vs Den |
| 28 | Rico Dowdle (Q) | Pit @ NO |
| 29 | Blake Corum | LAR @ LV |
| 30 | Kendre Miller | NO vs Pit |
| 31 | MarShawn Lloyd | GB @ Det |
| 32 | Tyjae Spears (Q) | Ten vs Cle |
| 33 | Kenneth Gainwell | TB @ Car |
| 34 | Bam Knight | Ari vs Den |
| 35 | Tyrone Tracy Jr. | NYG @ Hou |
| 36 | David Montgomery (Out) | Hou vs NYG |
| 37 | Jeremiyah Love (Out) | Ari vs Den |
| 38 | Kaelon Black | SF @ Atl |
| 39 | Mike Washington (Q) | LV vs LAR |
| 40 | George Holani | Sea vs KC |
