All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 11:58 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Car |
| 2 | Bijan Robinson | Atl @ NO |
| 3 | Jahmyr Gibbs | Det vs NYG |
| 4 | Jaxon Smith-Njigba | Sea @ Ten |
| 5 | Jonathan Taylor | Ind @ KC |
| 6 | James Cook | Buf @ Hou |
| 7 | Amon-Ra St. Brown | Det vs NYG |
| 8 | Puka Nacua | LAR vs TB |
| 9 | Saquon Barkley | Phi @ Dal |
| 10 | Derrick Henry | Bal vs NYJ |
| 11 | TreVeyon Henderson | NE @ Cin |
| 12 | Chase Brown | Cin vs NE |
| 13 | Rico Dowdle | Car @ SF |
| 14 | Breece Hall | NYJ @ Bal |
| 15 | Kyren Williams | LAR vs TB |
| 16 | Rashee Rice | KC vs Ind |
| 17 | CeeDee Lamb | Dal vs Phi |
| 18 | Trey McBride | Ari vs Jax |
| 19 | Travis Etienne (Q) | Jax @ Ari |
| 20 | Ashton Jeanty | LV vs Cle |
| 21 | Zay Flowers | Bal vs NYJ |
| 22 | Davante Adams | LAR vs TB |
| 23 | Tee Higgins | Cin vs NE |
| 24 | Emeka Egbuka (Q) | TB @ LAR |
| 25 | Javonte Williams | Dal vs Phi |
| 26 | Quinshon Judkins | Cle @ LV |
| 27 | Chris Olave | NO vs Atl |
| 28 | George Kittle | SF vs Car |
| 29 | Kenneth Walker III | Sea @ Ten |
| 30 | Emanuel Wilson | GB vs Min |
| 31 | D'Andre Swift (Q) | Chi vs Pit |
| 32 | Stefon Diggs | NE @ Cin |
| 33 | Alvin Kamara (Q) | NO vs Atl |
| 34 | Jameson Williams | Det vs NYG |
| 35 | Woody Marks | Hou vs Buf |
| Rank | Player | Match |
| 36 | George Pickens | Dal vs Phi |
| 37 | Nico Collins | Hou vs Buf |
| 38 | A.J. Brown | Phi @ Dal |
| 39 | Tetairoa McMillan | Car @ SF |
| 40 | Brock Bowers | LV vs Cle |
| 41 | DeVonta Smith | Phi @ Dal |
| 42 | David Montgomery | Det vs NYG |
| 43 | Justin Jefferson | Min @ GB |
| 44 | Michael Pittman Jr. | Ind @ KC |
| 45 | Rome Odunze | Chi vs Pit |
| 46 | Travis Kelce | KC vs Ind |
| 47 | Tyrone Tracy Jr. | NYG @ Det |
| 48 | Tyler Warren | Ind @ KC |
| 49 | Michael Wilson | Ari vs Jax |
| 50 | Jauan Jennings | SF vs Car |
| 51 | Mark Andrews | Bal vs NYJ |
| 52 | Jaylen Warren (Q) | Pit @ Chi |
| 53 | D.K. Metcalf | Pit @ Chi |
| 54 | Wan'Dale Robinson | NYG @ Det |
| 55 | Kenneth Gainwell | Pit @ Chi |
| 56 | Kyle Pitts | Atl @ NO |
| 57 | Khalil Shakir | Buf @ Hou |
| 58 | Alec Pierce | Ind @ KC |
| 59 | Jakobi Meyers | Jax @ Ari |
| 60 | Romeo Doubs (Q) | GB vs Min |
| 61 | Zach Charbonnet | Sea @ Ten |
| 62 | Hunter Henry | NE @ Cin |
| 63 | Rashid Shaheed | Sea @ Ten |
| 64 | Rachaad White | TB @ LAR |
| 65 | Xavier Worthy (Q) | KC vs Ind |
| 66 | Parker Washington | Jax @ Ari |
| 67 | Aaron Jones | Min @ GB |
| 68 | Juwan Johnson | NO vs Atl |
| 69 | Kareem Hunt | KC vs Ind |
| 70 | Ricky Pearsall | SF vs Car |
