All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 11:52 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs LAR |
| 2 | Jonathan Taylor | Ind vs Atl |
| 3 | Bijan Robinson | Atl @ Ind |
| 4 | De'Von Achane | Mia vs Buf |
| 5 | Jahmyr Gibbs | Det @ Wsh |
| 6 | James Cook | Buf @ Mia |
| 7 | Puka Nacua | LAR @ SF |
| 8 | Amon-Ra St. Brown | Det @ Wsh |
| 9 | Jaxon Smith-Njigba | Sea vs Ari |
| 10 | Josh Jacobs | GB vs Phi |
| 11 | Rico Dowdle (Q) | Car vs NO |
| 12 | Kyren Williams | LAR @ SF |
| 13 | Saquon Barkley | Phi @ GB |
| 14 | Drake London | Atl @ Ind |
| 15 | Justin Jefferson | Min vs Bal |
| 16 | Omarion Hampton | LAC vs Pit |
| 17 | Emeka Egbuka | TB vs NE |
| 18 | Bucky Irving | TB vs NE |
| 19 | Derrick Henry | Bal @ Min |
| 20 | Davante Adams | LAR @ SF |
| 21 | Breece Hall | NYJ vs Cle |
| 22 | Ashton Jeanty | LV @ Den |
| 23 | Quinshon Judkins | Cle @ NYJ |
| 24 | Zay Flowers | Bal @ Min |
| 25 | Travis Etienne | Jax @ Hou |
| 26 | Alvin Kamara (Q) | NO @ Car |
| 27 | J.K. Dobbins | Den vs LV |
| 28 | Brock Bowers | LV @ Den |
| 29 | Jaylen Warren | Pit @ LAC |
| 30 | Courtland Sutton | Den vs LV |
| 31 | Michael Pittman Jr. (Q) | Ind vs Atl |
| 32 | Jaylen Waddle | Mia vs Buf |
| 33 | Kenneth Walker III | Sea vs Ari |
| 34 | Nico Collins | Hou vs Jax |
| 35 | Ladd McConkey | LAC vs Pit |
| Rank | Player | Match |
| 36 | A.J. Brown | Phi @ GB |
| 37 | TreVeyon Henderson | NE @ TB |
| 38 | Deebo Samuel | Wsh vs Det |
| 39 | Chris Olave | NO @ Car |
| 40 | Rome Odunze | Chi vs NYG |
| 41 | Tyler Warren | Ind vs Atl |
| 42 | Trey McBride | Ari @ Sea |
| 43 | Stefon Diggs | NE @ TB |
| 44 | Garrett Wilson | NYJ vs Cle |
| 45 | D.K. Metcalf | Pit @ LAC |
| 46 | Sam LaPorta | Det @ Wsh |
| 47 | Tetairoa McMillan | Car vs NO |
| 48 | Kyle Monangai | Chi vs NYG |
| 49 | Khalil Shakir | Buf @ Mia |
| 50 | DeVonta Smith | Phi @ GB |
| 51 | David Montgomery | Det @ Wsh |
| 52 | Marvin Harrison Jr. | Ari @ Sea |
| 53 | Wan'Dale Robinson | NYG @ Chi |
| 54 | Romeo Doubs | GB vs Phi |
| 55 | Keenan Allen | LAC vs Pit |
| 56 | Jameson Williams | Det @ Wsh |
| 57 | Troy Franklin | Den vs LV |
| 58 | D'Andre Swift | Chi vs NYG |
| 59 | Oronde Gadsden | LAC vs Pit |
| 60 | Woody Marks | Hou vs Jax |
| 61 | Quentin Johnston | LAC vs Pit |
| 62 | Jordan Addison | Min vs Bal |
| 63 | Harold Fannin Jr. | Cle @ NYJ |
| 64 | Dalton Kincaid | Buf @ Mia |
| 65 | Aaron Jones | Min vs Bal |
| 66 | Rachaad White | TB vs NE |
| 67 | Jacory Croskey-Merritt (Q) | Wsh vs Det |
| 68 | Alec Pierce | Ind vs Atl |
| 69 | Tre Tucker | LV @ Den |
| 70 | Chris Godwin | TB vs NE |
