All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 12:36 PM ET.
| Rank | Player | Match |
| 1 | Trey McBride | Ari @ Sea |
| 2 | Sam LaPorta | Det @ Wsh |
| 3 | Oronde Gadsden | LAC vs Pit |
| 4 | Dalton Kincaid | Buf @ Mia |
| 5 | George Kittle | SF vs LAR |
| 6 | Hunter Henry | NE @ TB |
| 7 | David Njoku | Cle @ NYJ |
| 8 | Harold Fannin Jr. (Q) | Cle @ NYJ |
| 9 | Dallas Goedert | Phi @ GB |
| 10 | Zach Ertz | Wsh vs Det |
| 11 | Cade Otton | TB vs NE |
| 12 | Theo Johnson | NYG @ Chi |
| 13 | Juwan Johnson | NO @ Car |
| 14 | Mark Andrews | Bal @ Min |
| 15 | AJ Barner (Q) | Sea vs Ari |
| 16 | T.J. Hockenson | Min vs Bal |
| 17 | Dalton Schultz | Hou vs Jax |
| 18 | Mason Taylor | NYJ vs Cle |
| 19 | Colston Loveland | Chi vs NYG |
| 20 | Luke Musgrave | GB vs Phi |
| 21 | Isaiah Likely | Bal @ Min |
| 22 | Tyler Higbee | LAR @ SF |
| 23 | Pat Freiermuth | Pit @ LAC |
| 24 | Jonnu Smith | Pit @ LAC |
| 25 | Hunter Long (Out) | Jax @ Hou |
