All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 1:57 PM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF @ TB |
| 2 | Puka Nacua | LAR @ Bal |
| 3 | Jonathan Taylor | Ind vs Ari |
| 4 | Bijan Robinson | Atl vs Buf |
| 5 | Josh Jacobs | GB vs Cin |
| 6 | James Cook | Buf @ Atl |
| 7 | Saquon Barkley | Phi @ NYG |
| 8 | De'Von Achane | Mia vs LAC |
| 9 | Jahmyr Gibbs | Det @ KC |
| 10 | Javonte Williams | Dal @ Car |
| 11 | Kyren Williams | LAR @ Bal |
| 12 | Ashton Jeanty | LV vs Ten |
| 13 | Amon-Ra St. Brown (Q) | Det @ KC |
| 14 | Jaxon Smith-Njigba | Sea @ Jax |
| 15 | Quinshon Judkins | Cle @ Pit |
| 16 | Emeka Egbuka | TB vs SF |
| 17 | Breece Hall | NYJ vs Den |
| 18 | George Pickens | Dal @ Car |
| 19 | Rachaad White | TB vs SF |
| 20 | Davante Adams | LAR @ Bal |
| 21 | Derrick Henry | Bal vs LAR |
| 22 | Travis Etienne | Jax vs Sea |
| 23 | Ja'Marr Chase | Cin @ GB |
| 24 | Rico Dowdle | Car vs Dal |
| 25 | Tetairoa McMillan | Car vs Dal |
| 26 | Deebo Samuel | Wsh vs Chi |
| 27 | Jaylen Waddle | Mia vs LAC |
| 28 | Keenan Allen | LAC @ Mia |
| 29 | J.K. Dobbins | Den @ NYJ |
| 30 | Kenneth Walker III | Sea @ Jax |
| 31 | Drake London | Atl vs Buf |
| 32 | Courtland Sutton | Den @ NYJ |
| 33 | D'Andre Swift | Chi @ Wsh |
| 34 | Rome Odunze | Chi @ Wsh |
| 35 | Quentin Johnston (Q) | LAC @ Mia |
| Rank | Player | Match |
| 36 | Trey McBride | Ari @ Ind |
| 37 | D.K. Metcalf | Pit vs Cle |
| 38 | Jacory Croskey-Merritt | Wsh vs Chi |
| 39 | Garrett Wilson | NYJ vs Den |
| 40 | Marvin Harrison Jr. | Ari @ Ind |
| 41 | A.J. Brown | Phi @ NYG |
| 42 | Alvin Kamara (Q) | NO vs NE |
| 43 | Cam Skattebo | NYG vs Phi |
| 44 | Jakobi Meyers | LV vs Ten |
| 45 | Michael Pittman Jr. | Ind vs Ari |
| 46 | Zay Flowers (Q) | Bal vs LAR |
| 47 | Tyler Warren | Ind vs Ari |
| 48 | Xavier Worthy (P) | KC vs Det |
| 49 | Ladd McConkey | LAC @ Mia |
| 50 | Brian Thomas Jr. | Jax vs Sea |
| 51 | Jaylen Warren (P) | Pit vs Cle |
| 52 | David Montgomery | Det @ KC |
| 53 | Tony Pollard | Ten @ LV |
| 54 | Chris Olave | NO vs NE |
| 55 | Michael Carter | Ari @ Ind |
| 56 | Stefon Diggs | NE @ NO |
| 57 | Tucker Kraft (P) | GB vs Cin |
| 58 | Chris Godwin (Q) | TB vs SF |
| 59 | DeVonta Smith | Phi @ NYG |
| 60 | Chase Brown | Cin @ GB |
| 61 | Rhamondre Stevenson | NE @ NO |
| 62 | Jake Ferguson | Dal @ Car |
| 63 | Romeo Doubs | GB vs Cin |
| 64 | Tre Tucker | LV vs Ten |
| 65 | TreVeyon Henderson | NE @ NO |
| 66 | DJ Moore | Chi @ Wsh |
| 67 | Keon Coleman | Buf @ Atl |
| 68 | Travis Kelce | KC vs Det |
| 69 | Jerry Jeudy | Cle @ Pit |
| 70 | Darren Waller (Q) | Mia vs LAC |
