All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 1:03 PM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF @ TB |
| 2 | Puka Nacua | LAR @ Bal |
| 3 | Jonathan Taylor | Ind vs Ari |
| 4 | Josh Jacobs | GB vs Cin |
| 5 | Bijan Robinson | Atl vs Buf |
| 6 | James Cook | Buf @ Atl |
| 7 | De'Von Achane | Mia vs LAC |
| 8 | Jahmyr Gibbs | Det @ KC |
| 9 | Emeka Egbuka | TB vs SF |
| 10 | Kyren Williams | LAR @ Bal |
| 11 | Javonte Williams | Dal @ Car |
| 12 | Amon-Ra St. Brown | Det @ KC |
| 13 | Ashton Jeanty | LV vs Ten |
| 14 | Jaxon Smith-Njigba | Sea @ Jax |
| 15 | Rico Dowdle | Car vs Dal |
| 16 | Quinshon Judkins | Cle @ Pit |
| 17 | George Pickens | Dal @ Car |
| 18 | Rachaad White | TB vs SF |
| 19 | Davante Adams | LAR @ Bal |
| 20 | Derrick Henry | Bal vs LAR |
| 21 | Ja'Marr Chase (Q) | Cin @ GB |
| 22 | Travis Etienne | Jax vs Sea |
| 23 | Tetairoa McMillan | Car vs Dal |
| 24 | Deebo Samuel (Q) | Wsh vs Chi |
| 25 | Jaylen Waddle | Mia vs LAC |
| 26 | Keenan Allen | LAC @ Mia |
| 27 | Kenneth Walker III | Sea @ Jax |
| 28 | Jacory Croskey-Merritt | Wsh vs Chi |
| 29 | Drake London | Atl vs Buf |
| 30 | D'Andre Swift | Chi @ Wsh |
| 31 | Quentin Johnston (Q) | LAC @ Mia |
| 32 | Rome Odunze | Chi @ Wsh |
| 33 | D.K. Metcalf | Pit vs Cle |
| 34 | Trey McBride | Ari @ Ind |
| 35 | Marvin Harrison Jr. | Ari @ Ind |
| Rank | Player | Match |
| 36 | Alvin Kamara (Q) | NO vs NE |
| 37 | Michael Pittman Jr. | Ind vs Ari |
| 38 | Jakobi Meyers | LV vs Ten |
| 39 | Tyler Warren | Ind vs Ari |
| 40 | Zay Flowers (Q) | Bal vs LAR |
| 41 | Xavier Worthy | KC vs Det |
| 42 | Ladd McConkey | LAC @ Mia |
| 43 | Brian Thomas Jr. | Jax vs Sea |
| 44 | Tucker Kraft | GB vs Cin |
| 45 | Jaylen Warren | Pit vs Cle |
| 46 | David Montgomery | Det @ KC |
| 47 | Michael Carter | Ari @ Ind |
| 48 | Stefon Diggs | NE @ NO |
| 49 | Tony Pollard | Ten @ LV |
| 50 | Chris Olave | NO vs NE |
| 51 | Jake Ferguson | Dal @ Car |
| 52 | Romeo Doubs | GB vs Cin |
| 53 | Chase Brown | Cin @ GB |
| 54 | Rhamondre Stevenson | NE @ NO |
| 55 | Tre Tucker | LV vs Ten |
| 56 | TreVeyon Henderson | NE @ NO |
| 57 | Keon Coleman | Buf @ Atl |
| 58 | DJ Moore | Chi @ Wsh |
| 59 | Travis Kelce | KC vs Det |
| 60 | Jerry Jeudy | Cle @ Pit |
| 61 | Darren Waller | Mia vs LAC |
| 62 | Khalil Shakir | Buf @ Atl |
| 63 | Sam LaPorta | Det @ KC |
| 64 | Matthew Golden | GB vs Cin |
| 65 | Jameson Williams | Det @ KC |
| 66 | Kendrick Bourne | SF @ TB |
| 67 | Cooper Kupp | Sea @ Jax |
| 68 | Rashid Shaheed | NO vs NE |
| 69 | Hunter Henry | NE @ NO |
| 70 | Isiah Pacheco | KC vs Det |
