All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 1:56 PM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF @ TB |
| 2 | Jonathan Taylor | Ind vs Ari |
| 3 | Bijan Robinson | Atl vs Buf |
| 4 | Josh Jacobs | GB vs Cin |
| 5 | James Cook | Buf @ Atl |
| 6 | Saquon Barkley | Phi @ NYG |
| 7 | De'Von Achane | Mia vs LAC |
| 8 | Jahmyr Gibbs | Det @ KC |
| 9 | Javonte Williams | Dal @ Car |
| 10 | Kyren Williams | LAR @ Bal |
| 11 | Ashton Jeanty | LV vs Ten |
| 12 | Quinshon Judkins | Cle @ Pit |
| 13 | Breece Hall | NYJ vs Den |
| 14 | Rachaad White | TB vs SF |
| 15 | Derrick Henry | Bal vs LAR |
| 16 | Travis Etienne | Jax vs Sea |
| 17 | Rico Dowdle | Car vs Dal |
| 18 | J.K. Dobbins | Den @ NYJ |
| 19 | Kenneth Walker III | Sea @ Jax |
| 20 | D'Andre Swift | Chi @ Wsh |
| Rank | Player | Match |
| 21 | Jacory Croskey-Merritt | Wsh vs Chi |
| 22 | Alvin Kamara (Q) | NO vs NE |
| 23 | Cam Skattebo | NYG vs Phi |
| 24 | Jaylen Warren (P) | Pit vs Cle |
| 25 | David Montgomery | Det @ KC |
| 26 | Tony Pollard | Ten @ LV |
| 27 | Michael Carter | Ari @ Ind |
| 28 | Chase Brown | Cin @ GB |
| 29 | Rhamondre Stevenson | NE @ NO |
| 30 | TreVeyon Henderson | NE @ NO |
| 31 | Isiah Pacheco | KC vs Det |
| 32 | Hassan Haskins | LAC @ Mia |
| 33 | Zach Charbonnet | Sea @ Jax |
| 34 | Kenneth Gainwell | Pit vs Cle |
| 35 | Kareem Hunt (P) | KC vs Det |
| 36 | Kimani Vidal | LAC @ Mia |
| 37 | RJ Harvey | Den @ NYJ |
| 38 | Tyler Allgeier | Atl vs Buf |
| 39 | Bhayshul Tuten (Q) | Jax vs Sea |
| 40 | Blake Corum | LAR @ Bal |
