All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 1:03 PM ET.
| Rank | Player | Match |
| 1 | Puka Nacua | LAR @ Bal |
| 2 | Emeka Egbuka | TB vs SF |
| 3 | Amon-Ra St. Brown | Det @ KC |
| 4 | Jaxon Smith-Njigba | Sea @ Jax |
| 5 | George Pickens | Dal @ Car |
| 6 | Davante Adams | LAR @ Bal |
| 7 | Ja'Marr Chase (Q) | Cin @ GB |
| 8 | Tetairoa McMillan | Car vs Dal |
| 9 | Deebo Samuel (Q) | Wsh vs Chi |
| 10 | Jaylen Waddle | Mia vs LAC |
| 11 | Keenan Allen | LAC @ Mia |
| 12 | Drake London | Atl vs Buf |
| 13 | Quentin Johnston (Q) | LAC @ Mia |
| 14 | Rome Odunze | Chi @ Wsh |
| 15 | D.K. Metcalf | Pit vs Cle |
| 16 | Marvin Harrison Jr. | Ari @ Ind |
| 17 | Michael Pittman Jr. | Ind vs Ari |
| 18 | Jakobi Meyers | LV vs Ten |
| 19 | Zay Flowers (Q) | Bal vs LAR |
| 20 | Xavier Worthy | KC vs Det |
| 21 | Ladd McConkey | LAC @ Mia |
| 22 | Brian Thomas Jr. | Jax vs Sea |
| 23 | Stefon Diggs | NE @ NO |
| 24 | Chris Olave | NO vs NE |
| 25 | Romeo Doubs | GB vs Cin |
| Rank | Player | Match |
| 26 | Tre Tucker | LV vs Ten |
| 27 | Keon Coleman | Buf @ Atl |
| 28 | DJ Moore | Chi @ Wsh |
| 29 | Jerry Jeudy | Cle @ Pit |
| 30 | Khalil Shakir | Buf @ Atl |
| 31 | Matthew Golden | GB vs Cin |
| 32 | Jameson Williams | Det @ KC |
| 33 | Kendrick Bourne | SF @ TB |
| 34 | Cooper Kupp | Sea @ Jax |
| 35 | Rashid Shaheed | NO vs NE |
| 36 | Calvin Ridley | Ten @ LV |
| 37 | Tee Higgins | Cin @ GB |
| 38 | Malik Washington | Mia vs LAC |
| 39 | Marquise Brown | KC vs Det |
| 40 | Darnell Mooney (Q) | Atl vs Buf |
| 41 | Travis Hunter | Jax vs Sea |
| 42 | Sterling Shepard | TB vs SF |
| 43 | CeeDee Lamb (Out) | Dal @ Car |
| 44 | Alec Pierce | Ind vs Ari |
| 45 | Josh Downs | Ind vs Ari |
| 46 | Tyquan Thornton | KC vs Det |
| 47 | Tory Horton | Sea @ Jax |
| 48 | Elic Ayomanor | Ten @ LV |
| 49 | Isaiah Bond | Cle @ Pit |
| 50 | Tez Johnson | TB vs SF |
