All position ranks are: QB RB WR TE DEF
These rankings were updated as of Wed 8:21 PM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Jax |
| 2 | Jonathan Taylor | Ind @ LAR |
| 3 | Bijan Robinson | Atl vs Wsh |
| 4 | Jahmyr Gibbs | Det vs Cle |
| 5 | Josh Jacobs (Q) | GB @ Dal |
| 6 | Puka Nacua | LAR vs Ind |
| 7 | De'Von Achane | Mia vs NYJ |
| 8 | James Cook | Buf vs NO |
| 9 | Saquon Barkley | Phi @ TB |
| 10 | Derrick Henry | Bal @ KC |
| 11 | Kyren Williams | LAR vs Ind |
| 12 | Amon-Ra St. Brown | Det vs Cle |
| 13 | Bucky Irving | TB vs Phi |
| 14 | Nico Collins (Q) | Hou vs Ten |
| 15 | Ja'Marr Chase | Cin @ Den |
| 16 | Omarion Hampton | LAC @ NYG |
| 17 | Jordan Mason | Min @ Pit |
| 18 | Malik Nabers (Q) | NYG vs LAC |
| 19 | Justin Jefferson | Min @ Pit |
| 20 | Davante Adams | LAR vs Ind |
| 21 | Jaxon Smith-Njigba | Sea @ Ari |
| 22 | George Pickens | Dal vs GB |
| 23 | Chase Brown | Cin @ Den |
| 24 | Alvin Kamara | NO @ Buf |
| 25 | Courtland Sutton | Den vs Cin |
| 26 | Breece Hall | NYJ @ Mia |
| 27 | Chuba Hubbard | Car @ NE |
| 28 | J.K. Dobbins | Den vs Cin |
| 29 | Ashton Jeanty | LV vs Chi |
| 30 | Quinshon Judkins | Cle @ Det |
| 31 | Tyreek Hill | Mia vs NYJ |
| 32 | A.J. Brown | Phi @ TB |
| 33 | Tony Pollard | Ten @ Hou |
| 34 | Javonte Williams | Dal vs GB |
| 35 | Cam Skattebo | NYG vs LAC |
| Rank | Player | Match |
| 36 | Jaylen Warren | Pit vs Min |
| 37 | Kenneth Walker III | Sea @ Ari |
| 38 | Garrett Wilson | NYJ @ Mia |
| 39 | David Montgomery | Det vs Cle |
| 40 | Ricky Pearsall (Q) | SF vs Jax |
| 41 | Ladd McConkey | LAC @ NYG |
| 42 | D'Andre Swift (Q) | Chi @ LV |
| 43 | Drake London | Atl vs Wsh |
| 44 | Brian Thomas Jr. (P) | Jax @ SF |
| 45 | Trey McBride | Ari vs Sea |
| 46 | Emeka Egbuka | TB vs Phi |
| 47 | Trey Benson | Ari vs Sea |
| 48 | Tucker Kraft (Q) | GB @ Dal |
| 49 | Rome Odunze | Chi @ LV |
| 50 | Zay Flowers | Bal @ KC |
| 51 | Brock Bowers (P) | LV vs Chi |
| 52 | Tetairoa McMillan (Q) | Car @ NE |
| 53 | Keenan Allen | LAC @ NYG |
| 54 | Jakobi Meyers | LV vs Chi |
| 55 | Michael Pittman Jr. | Ind @ LAR |
| 56 | Travis Etienne | Jax @ SF |
| 57 | DeVonta Smith | Phi @ TB |
| 58 | Jameson Williams | Det vs Cle |
| 59 | Deebo Samuel | Wsh @ Atl |
| 60 | Nick Chubb | Hou vs Ten |
| 61 | DJ Moore | Chi @ LV |
| 62 | Jerry Jeudy | Cle @ Det |
| 63 | D.K. Metcalf | Pit vs Min |
| 64 | Tyler Warren | Ind @ LAR |
| 65 | Marvin Harrison Jr. | Ari vs Sea |
| 66 | Tee Higgins | Cin @ Den |
| 67 | Chris Olave | NO @ Buf |
| 68 | Jordan Addison | Min @ Pit |
| 69 | Jaylen Waddle | Mia vs NYJ |
| 70 | Quentin Johnston | LAC @ NYG |
