All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 9:57 AM ET.
| Rank | Player | Match |
| 1 | Alvin Kamara | NO vs LAR |
| 2 | Joe Mixon | Hou @ Jax |
| 3 | Christian McCaffrey | SF @ Buf |
| 4 | Bijan Robinson | Atl vs LAC |
| 5 | Ja'Marr Chase | Cin vs Pit |
| 6 | Saquon Barkley | Phi @ Bal |
| 7 | Chase Brown | Cin vs Pit |
| 8 | Derrick Henry | Bal vs Phi |
| 9 | Kyren Williams | LAR @ NO |
| 10 | Breece Hall (Q) | NYJ vs Sea |
| 11 | Justin Jefferson | Min vs Ari |
| 12 | Puka Nacua | LAR @ NO |
| 13 | Nico Collins | Hou @ Jax |
| 14 | A.J. Brown | Phi @ Bal |
| 15 | Kenneth Walker III | Sea @ NYJ |
| 16 | Tee Higgins | Cin vs Pit |
| 17 | Jonathan Taylor | Ind @ NE |
| 18 | Cooper Kupp | LAR @ NO |
| 19 | Aaron Jones | Min vs Ari |
| 20 | Chuba Hubbard | Car vs TB |
| 21 | Mike Evans | TB @ Car |
| 22 | George Pickens | Pit @ Cin |
| 23 | James Cook | Buf vs SF |
| 24 | James Conner | Ari @ Min |
| 25 | Tony Pollard | Ten @ Wsh |
| 26 | Drake London | Atl vs LAC |
| 27 | Ladd McConkey | LAC @ Atl |
| 28 | Davante Adams | NYJ vs Sea |
| 29 | Terry McLaurin | Wsh vs Ten |
| 30 | Courtland Sutton | Den vs Cle |
| 31 | Zay Flowers | Bal vs Phi |
| 32 | Garrett Wilson | NYJ vs Sea |
| 33 | Rhamondre Stevenson | NE vs Ind |
| 34 | Jaxon Smith-Njigba | Sea @ NYJ |
| 35 | Bucky Irving | TB @ Car |
| Rank | Player | Match |
| 36 | Trey McBride | Ari @ Min |
| 37 | Brian Thomas Jr. | Jax vs Hou |
| 38 | George Kittle | SF @ Buf |
| 39 | DK Metcalf | Sea @ NYJ |
| 40 | Brian Robinson | Wsh vs Ten |
| 41 | Jauan Jennings | SF @ Buf |
| 42 | Najee Harris | Pit @ Cin |
| 43 | Nick Chubb | Cle @ Den |
| 44 | Calvin Ridley | Ten @ Wsh |
| 45 | Taysom Hill | NO vs LAR |
| 46 | Darnell Mooney | Atl vs LAC |
| 47 | Jerry Jeudy | Cle @ Den |
| 48 | Rachaad White | TB @ Car |
| 49 | Tank Dell | Hou @ Jax |
| 50 | Marvin Harrison Jr. | Ari @ Min |
| 51 | Michael Pittman Jr. | Ind @ NE |
| 52 | Jordan Addison | Min vs Ari |
| 53 | Khalil Shakir | Buf vs SF |
| 54 | Deebo Samuel | SF @ Buf |
| 55 | Nick Westbrook | Ten @ Wsh |
| 56 | Gus Edwards | LAC @ Atl |
| 57 | Evan Engram | Jax vs Hou |
| 58 | T.J. Hockenson | Min vs Ari |
| 59 | Jaylen Warren | Pit @ Cin |
| 60 | Cade Otton | TB @ Car |
| 61 | Quentin Johnston | LAC @ Atl |
| 62 | DeVonta Smith (Q) | Phi @ Bal |
| 63 | David Njoku | Cle @ Den |
| 64 | Xavier Legette | Car vs TB |
| 65 | Javonte Williams | Den vs Cle |
| 66 | Amari Cooper | Buf vs SF |
| 67 | Hunter Henry | NE vs Ind |
| 68 | Travis Etienne | Jax vs Hou |
| 69 | Adam Thielen | Car vs TB |
| 70 | DeMario Douglas (Q) | NE vs Ind |
