All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 9:57 AM ET.
| Rank | Player | Match |
| 1 | Ja'Marr Chase | Cin vs Pit |
| 2 | Justin Jefferson | Min vs Ari |
| 3 | Puka Nacua | LAR @ NO |
| 4 | Nico Collins | Hou @ Jax |
| 5 | A.J. Brown | Phi @ Bal |
| 6 | Tee Higgins | Cin vs Pit |
| 7 | Cooper Kupp | LAR @ NO |
| 8 | Mike Evans | TB @ Car |
| 9 | George Pickens | Pit @ Cin |
| 10 | Drake London | Atl vs LAC |
| 11 | Ladd McConkey | LAC @ Atl |
| 12 | Davante Adams | NYJ vs Sea |
| 13 | Terry McLaurin | Wsh vs Ten |
| 14 | Courtland Sutton | Den vs Cle |
| 15 | Zay Flowers | Bal vs Phi |
| 16 | Garrett Wilson | NYJ vs Sea |
| 17 | Jaxon Smith-Njigba | Sea @ NYJ |
| 18 | Brian Thomas Jr. | Jax vs Hou |
| 19 | DK Metcalf | Sea @ NYJ |
| 20 | Jauan Jennings | SF @ Buf |
| 21 | Calvin Ridley | Ten @ Wsh |
| 22 | Darnell Mooney | Atl vs LAC |
| 23 | Jerry Jeudy | Cle @ Den |
| 24 | Tank Dell | Hou @ Jax |
| 25 | Marvin Harrison Jr. | Ari @ Min |
| Rank | Player | Match |
| 26 | Michael Pittman Jr. | Ind @ NE |
| 27 | Jordan Addison | Min vs Ari |
| 28 | Khalil Shakir | Buf vs SF |
| 29 | Deebo Samuel | SF @ Buf |
| 30 | Nick Westbrook | Ten @ Wsh |
| 31 | Quentin Johnston | LAC @ Atl |
| 32 | DeVonta Smith (Q) | Phi @ Bal |
| 33 | Xavier Legette | Car vs TB |
| 34 | Amari Cooper | Buf vs SF |
| 35 | Adam Thielen | Car vs TB |
| 36 | DeMario Douglas (Q) | NE vs Ind |
| 37 | Rashod Bateman | Bal vs Phi |
| 38 | Noah Brown | Wsh vs Ten |
| 39 | Alec Pierce (Q) | Ind @ NE |
| 40 | Marquez Valdes-Scantling | NO vs LAR |
| 41 | Devaughn Vele | Den vs Cle |
| 42 | Elijah Moore | Cle @ Den |
| 43 | Joshua Palmer | LAC @ Atl |
| 44 | Keon Coleman (Q) | Buf vs SF |
| 45 | Nick Westbrook-Ikhine | Ten @ Wsh |
| 46 | David Moore | Car vs TB |
| 47 | Tyler Lockett | Sea @ NYJ |
| 48 | Michael Wilson | Ari @ Min |
| 49 | Cedric Tillman (Q) | Cle @ Den |
| 50 | Demarcus Robinson | LAR @ NO |
