All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 9:48 AM ET.
| Rank | Player | Match |
| 1 | Amon-Ra St. Brown | Det vs Chi |
| 2 | Justin Jefferson | Min @ Chi |
| 3 | A.J. Brown | Phi @ LAR |
| 4 | Nico Collins | Hou vs Ten |
| 5 | Tyreek Hill | Mia vs NE |
| 6 | Puka Nacua | LAR vs Phi |
| 7 | CeeDee Lamb | Dal @ Wsh |
| 8 | DK Metcalf | Sea vs Ari |
| 9 | Cooper Kupp | LAR vs Phi |
| 10 | Terry McLaurin | Wsh vs Dal |
| 11 | Mike Evans (Q) | TB @ NYG |
| 12 | Jaxon Smith-Njigba | Sea vs Ari |
| 13 | Malik Nabers (Q) | NYG vs TB |
| 14 | Ladd McConkey (Q) | LAC vs Bal |
| 15 | Zay Flowers | Bal @ LAC |
| 16 | Courtland Sutton | Den @ LV |
| 17 | Marvin Harrison Jr. | Ari @ Sea |
| 18 | Jayden Reed | GB vs SF |
| 19 | Calvin Ridley | Ten @ Hou |
| 20 | Josh Downs | Ind vs Det |
| 21 | Deebo Samuel | SF @ GB |
| 22 | Jauan Jennings | SF @ GB |
| 23 | Tank Dell | Hou vs Ten |
| 24 | Jakobi Meyers | LV vs Den |
| 25 | Jameson Williams | Det vs Chi |
| Rank | Player | Match |
| 26 | Quentin Johnston | LAC vs Bal |
| 27 | DeAndre Hopkins | KC @ Car |
| 28 | DJ Moore | Chi vs Min |
| 29 | Nick Westbrook | Ten @ Hou |
| 30 | Jaylen Waddle | Mia vs NE |
| 31 | Xavier Worthy | KC @ Car |
| 32 | Christian Watson | GB vs SF |
| 33 | Michael Pittman Jr. | Ind vs Det |
| 34 | Romeo Doubs | GB vs SF |
| 35 | Jordan Addison | Min @ Chi |
| 36 | Rome Odunze | Chi vs Min |
| 37 | Tyler Lockett | Sea vs Ari |
| 38 | Keenan Allen (Q) | Chi vs Min |
| 39 | Wan'Dale Robinson | NYG vs TB |
| 40 | DeMario Douglas | NE @ Mia |
| 41 | Rashod Bateman (Q) | Bal @ LAC |
| 42 | Joshua Palmer | LAC vs Bal |
| 43 | Noah Brown | Wsh vs Dal |
| 44 | Darius Slayton | NYG vs TB |
| 45 | Xavier Legette | Car vs KC |
| 46 | Adam Thielen (Q) | Car vs KC |
| 47 | Alec Pierce | Ind vs Det |
| 48 | Michael Wilson | Ari @ Sea |
| 49 | Nick Westbrook-Ikhine | Ten @ Hou |
| 50 | Demarcus Robinson | LAR vs Phi |
