All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 9:58 AM ET.
| Rank | Player | Match |
| 1 | Austin Ekeler | LAC vs Mia |
| 2 | Justin Jefferson | Min vs TB |
| 3 | Christian McCaffrey | SF @ Pit |
| 4 | Tony Pollard | Dal @ NYG |
| 5 | Tyreek Hill | Mia @ LAC |
| 6 | Bijan Robinson | Atl vs Car |
| 7 | Saquon Barkley | NYG vs Dal |
| 8 | Nick Chubb | Cle vs Cin |
| 9 | Ja'Marr Chase | Cin @ Cle |
| 10 | CeeDee Lamb | Dal @ NYG |
| 11 | Derrick Henry | Ten @ NO |
| 12 | Stefon Diggs | Buf @ NYJ |
| 13 | Amon-Ra St. Brown | Det @ KC |
| 14 | Josh Jacobs | LV @ Den |
| 15 | A.J. Brown | Phi @ NE |
| 16 | Davante Adams | LV @ Den |
| 17 | Garrett Wilson | NYJ vs Buf |
| 18 | Joe Mixon | Cin @ Cle |
| 19 | Rhamondre Stevenson | NE vs Phi |
| 20 | Jaylen Waddle (GTD) | Mia @ LAC |
| 21 | Aaron Jones | GB @ Chi |
| 22 | Travis Etienne | Jax @ Ind |
| 23 | Chris Olave | NO vs Ten |
| 24 | Alexander Mattison | Min vs TB |
| 25 | D.K. Metcalf | Sea vs LAR |
| 26 | Calvin Ridley | Jax @ Ind |
| 27 | Kenneth Walker III | Sea vs LAR |
| 28 | Keenan Allen | LAC vs Mia |
| 29 | Christian Watson (GTD) | GB @ Chi |
| 30 | Tee Higgins | Cin @ Cle |
| 31 | Amari Cooper | Cle vs Cin |
| 32 | Tyler Lockett | Sea vs LAR |
| 33 | Rachaad White | TB @ Min |
| 34 | D.J. Moore | Chi vs GB |
| 35 | Dameon Pierce | Hou @ Bal |
| Rank | Player | Match |
| 36 | J.K. Dobbins | Bal vs Hou |
| 37 | DeVonta Smith | Phi @ NE |
| 38 | Jahmyr Gibbs | Det @ KC |
| 39 | James Conner | Ari @ Wsh |
| 40 | Christian Kirk | Jax @ Ind |
| 41 | Chris Godwin | TB @ Min |
| 42 | Mike Evans | TB @ Min |
| 43 | Miles Sanders | Car @ Atl |
| 44 | Deebo Samuel | SF @ Pit |
| 45 | Najee Harris | Pit vs SF |
| 46 | Mike Williams | LAC vs Mia |
| 47 | Courtland Sutton | Den vs LV |
| 48 | Terry McLaurin (GTD) | Wsh vs Ari |
| 49 | Mark Andrews (GTD) | Bal vs Hou |
| 50 | Isiah Pacheco | KC vs Det |
| 51 | Drake London | Atl vs Car |
| 52 | T.J. Hockenson | Min vs TB |
| 53 | Raheem Mostert | Mia @ LAC |
| 54 | Jahan Dotson | Wsh vs Ari |
| 55 | DeAndre Hopkins | Ten @ NO |
| 56 | Cam Akers | LAR @ Sea |
| 57 | David Montgomery | Det @ KC |
| 58 | Diontae Johnson | Pit vs SF |
| 59 | Dalvin Cook | NYJ vs Buf |
| 60 | Michael Pittman Jr. | Ind vs Jax |
| 61 | Antonio Gibson | Wsh vs Ari |
| 62 | Samaje Perine | Den vs LV |
| 63 | Brandon Aiyuk | SF @ Pit |
| 64 | George Pickens | Pit vs SF |
| 65 | Breece Hall (GTD) | NYJ vs Buf |
| 66 | Brandin Cooks | Dal @ NYG |
| 67 | Javonte Williams | Den vs LV |
| 68 | Marquise Brown (GTD) | Ari @ Wsh |
| 69 | James Cook | Buf @ NYJ |
| 70 | Khalil Herbert | Chi vs GB |
