All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:15 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | Car @ Mia |
| 2 | Jonathan Taylor | Ind vs TB |
| 3 | Cooper Kupp | LAR @ GB |
| 4 | Austin Ekeler | LAC @ Den |
| 5 | Dalvin Cook | Min @ SF |
| 6 | Davante Adams | GB vs LAR |
| 7 | Najee Harris | Pit @ Cin |
| 8 | Deebo Samuel | SF vs Min |
| 9 | Joe Mixon | Cin vs Pit |
| 10 | Justin Jefferson | Min @ SF |
| 11 | Saquon Barkley (Q) | NYG vs Phi |
| 12 | James Robinson | Jax vs Atl |
| 13 | Chris Godwin | TB @ Ind |
| 14 | Ja'Marr Chase | Cin vs Pit |
| 15 | Cordarrelle Patterson (GTD) | Atl @ Jax |
| 16 | Keenan Allen | LAC @ Den |
| 17 | Darrell Henderson | LAR @ GB |
| 18 | Mike Evans | TB @ Ind |
| 19 | Leonard Fournette | TB @ Ind |
| 20 | Nick Chubb | Cle @ Bal |
| 21 | Diontae Johnson | Pit @ Cin |
| 22 | D.K. Metcalf | Sea @ Wsh |
| 23 | Antonio Gibson | Wsh vs Sea |
| 24 | Tyler Lockett | Sea @ Wsh |
| 25 | Marquise Brown (GTD) | Bal vs Cle |
| 26 | George Kittle | SF vs Min |
| 27 | Terry McLaurin | Wsh vs Sea |
| 28 | Adam Thielen | Min @ SF |
| 29 | Brandin Cooks | Hou vs NYJ |
| 30 | D.J. Moore | Car @ Mia |
| 31 | Myles Gaskin | Mia vs Car |
| 32 | Miles Sanders | Phi @ NYG |
| 33 | Michael Pittman Jr. | Ind vs TB |
| 34 | Mark Andrews | Bal vs Cle |
| 35 | Kyle Pitts | Atl @ Jax |
| Rank | Player | Match |
| 36 | DeVonta Smith | Phi @ NYG |
| 37 | Mike Williams | LAC @ Den |
| 38 | Jaylen Waddle | Mia vs Car |
| 39 | Elijah Moore | NYJ @ Hou |
| 40 | Melvin Gordon | Den vs LAC |
| 41 | Chase Claypool | Pit @ Cin |
| 42 | Eli Mitchell (GTD) | SF vs Min |
| 43 | Tee Higgins | Cin vs Pit |
| 44 | Brandon Aiyuk | SF vs Min |
| 45 | Jerry Jeudy | Den vs LAC |
| 46 | A.J. Dillon | GB vs LAR |
| 47 | Aaron Jones (GTD) | GB vs LAR |
| 48 | Javonte Williams | Den vs LAC |
| 49 | Marvin Jones | Jax vs Atl |
| 50 | Kenny Golladay | NYG vs Phi |
| 51 | David Johnson | Hou vs NYJ |
| 52 | Rhamondre Stevenson (GTD) | NE vs Ten |
| 53 | Kareem Hunt | Cle @ Bal |
| 54 | Ty Johnson | NYJ @ Hou |
| 55 | Jarvis Landry (GTD) | Cle @ Bal |
| 56 | Devonta Freeman | Bal vs Cle |
| 57 | Courtland Sutton | Den vs LAC |
| 58 | Damien Harris | NE vs Ten |
| 59 | Jakobi Meyers | NE vs Ten |
| 60 | D'Onta Foreman | Ten @ NE |
| 61 | Dallas Goedert | Phi @ NYG |
| 62 | Jamison Crowder | NYJ @ Hou |
| 63 | Van Jefferson | LAR @ GB |
| 64 | Odell Beckham | LAR @ GB |
| 65 | Dontrell Hilliard | Ten @ NE |
| 66 | Rob Gronkowski | TB @ Ind |
| 67 | Alex Collins | Sea @ Wsh |
| 68 | Mike Gesicki | Mia vs Car |
| 69 | Laviska Shenault | Jax vs Atl |
| 70 | Rashod Bateman | Bal vs Cle |
