All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 10:27 AM ET.
| Rank | Player | Match |
| 1 | Derrick Henry | Ten @ Ind |
| 2 | Dalvin Cook | Min vs Dal |
| 3 | Cooper Kupp | LAR @ Hou |
| 4 | Alvin Kamara | NO vs TB |
| 5 | Darrell Henderson | LAR @ Hou |
| 6 | Tyreek Hill | KC vs NYG |
| 7 | D'Andre Swift | Det vs Phi |
| 8 | Najee Harris | Pit @ Cle |
| 9 | Jonathan Taylor | Ind vs Ten |
| 10 | Nick Chubb | Cle vs Pit |
| 11 | Austin Ekeler (GTD) | LAC vs NE |
| 12 | Stefon Diggs | Buf vs Mia |
| 13 | Ezekiel Elliott | Dal @ Min |
| 14 | A.J. Brown | Ten @ Ind |
| 15 | Joe Mixon | Cin @ NYJ |
| 16 | Justin Jefferson | Min vs Dal |
| 17 | Ja'Marr Chase | Cin @ NYJ |
| 18 | Travis Kelce | KC vs NYG |
| 19 | James Robinson | Jax @ Sea |
| 20 | D.J. Moore | Car @ Atl |
| 21 | Deebo Samuel | SF @ Chi |
| 22 | Chris Godwin | TB @ NO |
| 23 | Chuba Hubbard | Car @ Atl |
| 24 | Calvin Ridley | Atl vs Car |
| 25 | Cordarrelle Patterson | Atl vs Car |
| 26 | Mike Williams | LAC vs NE |
| 27 | Mike Evans | TB @ NO |
| 28 | Robert Woods | LAR @ Hou |
| 29 | Leonard Fournette | TB @ NO |
| 30 | D.K. Metcalf | Sea vs Jax |
| 31 | Terry McLaurin (GTD) | Wsh @ Den |
| 32 | DeVonta Smith | Phi @ Det |
| 33 | Keenan Allen | LAC vs NE |
| 34 | CeeDee Lamb | Dal @ Min |
| 35 | Michael Pittman Jr. | Ind vs Ten |
| Rank | Player | Match |
| 36 | Diontae Johnson | Pit @ Cle |
| 37 | Antonio Gibson | Wsh @ Den |
| 38 | Darrel Williams | KC vs NYG |
| 39 | Khalil Herbert | Chi vs SF |
| 40 | Adam Thielen | Min vs Dal |
| 41 | Damien Harris | NE @ LAC |
| 42 | Devontae Booker | NYG @ KC |
| 43 | Tee Higgins | Cin @ NYJ |
| 44 | Courtland Sutton | Den vs Wsh |
| 45 | Brandin Cooks | Hou vs LAR |
| 46 | Sterling Shepard (GTD) | NYG @ KC |
| 47 | Michael Carter | NYJ vs Cin |
| 48 | Amari Cooper | Dal @ Min |
| 49 | Kenneth Gainwell | Phi @ Det |
| 50 | Marvin Jones | Jax @ Sea |
| 51 | Eli Mitchell | SF @ Chi |
| 52 | Tyler Lockett | Sea vs Jax |
| 53 | Alex Collins (GTD) | Sea vs Jax |
| 54 | Javonte Williams | Den vs Wsh |
| 55 | Kyle Pitts | Atl vs Car |
| 56 | Myles Gaskin | Mia @ Buf |
| 57 | Melvin Gordon | Den vs Wsh |
| 58 | Jakobi Meyers | NE @ LAC |
| 59 | Emmanuel Sanders | Buf vs Mia |
| 60 | Kadarius Toney (GTD) | NYG @ KC |
| 61 | Jerry Jeudy (GTD) | Den vs Wsh |
| 62 | Zack Moss | Buf vs Mia |
| 63 | Chase Claypool | Pit @ Cle |
| 64 | Jaylen Waddle | Mia @ Buf |
| 65 | T.J. Hockenson | Det vs Phi |
| 66 | Cole Beasley | Buf vs Mia |
| 67 | Jamison Crowder | NYJ vs Cin |
| 68 | Dallas Goedert | Phi @ Det |
| 69 | David Johnson | Hou vs LAR |
| 70 | Robby Anderson | Car @ Atl |
