All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 1:15 PM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | Car vs NYJ |
| 2 | Dalvin Cook | Min @ Cin |
| 3 | Alvin Kamara | NO vs GB |
| 4 | Derrick Henry | Ten vs Ari |
| 5 | Tyreek Hill | KC vs Cle |
| 6 | Davante Adams | GB @ NO |
| 7 | Calvin Ridley | Atl vs Phi |
| 8 | Travis Kelce | KC vs Cle |
| 9 | DeAndre Hopkins | Ari @ Ten |
| 10 | Stefon Diggs | Buf vs Pit |
| 11 | Aaron Jones | GB @ NO |
| 12 | Jonathan Taylor | Ind vs Sea |
| 13 | Austin Ekeler (GTD) | LAC @ Wsh |
| 14 | Joe Mixon | Cin vs Min |
| 15 | D.K. Metcalf | Sea @ Ind |
| 16 | Antonio Gibson | Wsh vs LAC |
| 17 | Ezekiel Elliott | Dal @ TB |
| 18 | Saquon Barkley | NYG vs Den |
| 19 | Najee Harris | Pit @ Buf |
| 20 | A.J. Brown (GTD) | Ten vs Ari |
| 21 | Nick Chubb | Cle @ KC |
| 22 | Clyde Edwards-Helaire | KC vs Cle |
| 23 | Justin Jefferson | Min @ Cin |
| 24 | Chris Carson | Sea @ Ind |
| 25 | James Robinson | Jax @ Hou |
| 26 | Terry McLaurin | Wsh vs LAC |
| 27 | David Montgomery | Chi @ LAR |
| 28 | CeeDee Lamb | Dal @ TB |
| 29 | Miles Sanders | Phi @ Atl |
| 30 | Keenan Allen | LAC @ Wsh |
| 31 | Darren Waller | LV vs Bal |
| 32 | George Kittle | SF @ Det |
| 33 | Tyler Lockett | Sea @ Ind |
| 34 | Mike Evans | TB vs Dal |
| 35 | Adam Thielen | Min @ Cin |
| Rank | Player | Match |
| 36 | Chris Godwin | TB vs Dal |
| 37 | Robert Woods | LAR vs Chi |
| 38 | Amari Cooper | Dal @ TB |
| 39 | Mike Davis | Atl vs Phi |
| 40 | Cooper Kupp | LAR vs Chi |
| 41 | Tee Higgins | Cin vs Min |
| 42 | D'Andre Swift | Det vs SF |
| 43 | Allen Robinson | Chi @ LAR |
| 44 | Julio Jones | Ten vs Ari |
| 45 | D.J. Moore | Car vs NYJ |
| 46 | Darrell Henderson (GTD) | LAR vs Chi |
| 47 | Raheem Mostert | SF @ Det |
| 48 | Josh Jacobs | LV vs Bal |
| 49 | Gus Edwards | Bal @ LV |
| 50 | Brandon Aiyuk (GTD) | SF @ Det |
| 51 | Chase Claypool | Pit @ Buf |
| 52 | Deebo Samuel | SF @ Det |
| 53 | Mark Andrews | Bal @ LV |
| 54 | Odell Beckham (GTD) | Cle @ KC |
| 55 | Jerry Jeudy | Den @ NYG |
| 56 | Laviska Shenault | Jax @ Hou |
| 57 | Chase Edmonds | Ari @ Ten |
| 58 | Damien Harris | NE vs Mia |
| 59 | Diontae Johnson | Pit @ Buf |
| 60 | Myles Gaskin | Mia @ NE |
| 61 | Robby Anderson | Car vs NYJ |
| 62 | Marvin Jones | Jax @ Hou |
| 63 | Corey Davis | NYJ @ Car |
| 64 | Ja'Marr Chase | Cin vs Min |
| 65 | Brandin Cooks | Hou vs Jax |
| 66 | Kenny Golladay | NYG vs Den |
| 67 | Tyler Boyd | Cin vs Min |
| 68 | Kyle Pitts | Atl vs Phi |
| 69 | Antonio Brown | TB vs Dal |
| 70 | Marquise Brown (GTD) | Bal @ LV |
