All position ranks are: QB RB WR TE FLEX D
These rankings were updated as of Sun 11:06 AM ET.
| Rank | Player | Match |
| 1 | Alvin Kamara | NO vs GB |
| 2 | Ezekiel Elliott | Dal @ Sea |
| 3 | Miles Sanders | Phi vs Cin |
| 4 | DeAndre Hopkins | Ari vs Det |
| 5 | Derrick Henry | Ten @ Min |
| 6 | Dalvin Cook | Min vs Ten |
| 7 | Aaron Jones | GB @ NO |
| 8 | Jonathan Taylor | Ind vs NYJ |
| 9 | Kenyan Drake | Ari vs Det |
| 10 | Chris Carson | Sea vs Dal |
| 11 | Austin Ekeler | LAC vs Car |
| 12 | Josh Jacobs (que) | LV @ NE |
| 13 | Clyde Edwards-Helaire | KC @ Bal |
| 14 | Joe Mixon | Cin @ Phi |
| 15 | James Conner | Pit vs Hou |
| 16 | Nick Chubb | Cle vs Wsh |
| 17 | Devin Singletary | Buf vs LAR |
| 18 | Melvin Gordon | Den vs TB |
| 19 | Travis Kelce | KC @ Bal |
| 20 | Todd Gurley | Atl vs Chi |
| 21 | Tyler Lockett | Sea vs Dal |
| 22 | Calvin Ridley | Atl vs Chi |
| 23 | Tyreek Hill | KC @ Bal |
| 24 | D.K. Metcalf | Sea vs Dal |
| 25 | Amari Cooper | Dal @ Sea |
| 26 | D.J. Moore | Car @ LAC |
| 27 | Mike Evans | TB @ Den |
| 28 | Adam Thielen | Min vs Ten |
| 29 | Allen Robinson | Chi @ Atl |
| 30 | Chris Godwin | TB @ Den |
| 31 | David Johnson | Hou @ Pit |
| 32 | Odell Beckham | Cle vs Wsh |
| 33 | Stefon Diggs | Buf vs LAR |
| 34 | Mark Andrews | Bal vs KC |
| 35 | Terry McLaurin | Wsh @ Cle |
| Rank | Player | Match |
| 36 | Keenan Allen | LAC vs Car |
| 37 | Robert Woods | LAR @ Buf |
| 38 | JuJu Smith-Schuster | Pit vs Hou |
| 39 | Jerick McKinnon | SF @ NYG |
| 40 | David Montgomery (GTD) | Chi @ Atl |
| 41 | Julian Edelman (que) | NE vs LV |
| 42 | Cooper Kupp | LAR @ Buf |
| 43 | Diontae Johnson (GTD) | Pit vs Hou |
| 44 | Marquise Brown | Bal vs KC |
| 45 | Julio Jones (que) | Atl vs Chi |
| 46 | Kareem Hunt | Cle vs Wsh |
| 47 | T.Y. Hilton | Ind vs NYJ |
| 48 | Kenny Golladay (GTD) | Det @ Ari |
| 49 | Darren Waller (que) | LV @ NE |
| 50 | Michael Gallup | Dal @ Sea |
| 51 | Mike Davis | Car @ LAC |
| 52 | Marvin Jones (GTD) | Det @ Ari |
| 53 | Darrell Henderson | LAR @ Buf |
| 54 | A.J. Green | Cin @ Phi |
| 55 | Tyler Boyd | Cin @ Phi |
| 56 | Zach Ertz | Phi vs Cin |
| 57 | Darius Slayton | NYG vs SF |
| 58 | DeSean Jackson | Phi vs Cin |
| 59 | Jarvis Landry | Cle vs Wsh |
| 60 | Robby Anderson | Car @ LAC |
| 61 | N'Keal Harry (que) | NE vs LV |
| 62 | CeeDee Lamb | Dal @ Sea |
| 63 | Will Fuller | Hou @ Pit |
| 64 | Mark Ingram | Bal vs KC |
| 65 | John Brown | Buf vs LAR |
| 66 | Corey Davis | Ten @ Min |
| 67 | Hunter Henry | LAC vs Car |
| 68 | Allen Lazard | GB @ NO |
| 69 | Evan Engram | NYG vs SF |
| 70 | T.J. Hockenson | Det @ Ari |
