All position rankings are: QB | RB | WR | TE | FLEX | D
These rankings were updated as of Sun 10:42 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | Car @ Ind |
| 2 | Michael Thomas | NO @ Ten |
| 3 | Saquon Barkley | NYG @ Wsh |
| 4 | Ezekiel Elliott | Dal @ Phi |
| 5 | Leonard Fournette | Jax @ Atl |
| 6 | Chris Carson | Sea vs Ari |
| 7 | Alvin Kamara | NO @ Ten |
| 8 | Julio Jones | Atl vs Jax |
| 9 | Davante Adams | GB @ Min |
| 10 | Tyreek Hill | KC @ Chi |
| 11 | Joe Mixon | Cin @ Mia |
| 12 | Melvin Gordon | LAC vs Oak |
| 13 | Le'Veon Bell | NYJ vs Pit |
| 14 | Amari Cooper | Dal @ Phi |
| 15 | Tyler Lockett | Sea vs Ari |
| 16 | Aaron Jones | GB @ Min |
| 17 | Devonta Freeman | Atl vs Jax |
| 18 | Zach Ertz | Phi vs Dal |
| 19 | Travis Kelce | KC @ Chi |
| 20 | James Conner | Pit @ NYJ |
| 21 | Kenyan Drake | Ari @ Sea |
| 22 | Miles Sanders | Phi vs Dal |
| 23 | Nick Chubb | Cle vs Bal |
| 24 | Austin Ekeler | LAC vs Oak |
| 25 | Keenan Allen | LAC vs Oak |
| 26 | Allen Robinson | Chi vs KC |
| 27 | D.J. Moore | Car @ Ind |
| 28 | Mark Ingram | Bal @ Cle |
| 29 | DeVante Parker | Mia vs Cin |
| 30 | Marlon Mack | Ind vs Car |
| 31 | Stefon Diggs | Min vs GB |
| 32 | Courtland Sutton | Den vs Det |
| 33 | A.J. Brown | Ten vs NO |
| 34 | Phillip Lindsay | Den vs Det |
| 35 | Tyler Boyd | Cin @ Mia |
| Rank | Player | Match |
| 36 | Kenny Golladay | Det @ Den |
| 37 | Jarvis Landry | Cle vs Bal |
| 38 | DeAndre Washington | Oak @ LAC |
| 39 | Mark Andrews | Bal @ Cle |
| 40 | Adam Thielen | Min vs GB |
| 41 | T.Y. Hilton | Ind vs Car |
| 42 | D.J. Chark (que) | Jax @ Atl |
| 43 | Darren Waller | Oak @ LAC |
| 44 | Terry McLaurin | Wsh vs NYG |
| 45 | Austin Hooper | Atl vs Jax |
| 46 | Michael Gallup | Dal @ Phi |
| 47 | D.K. Metcalf | Sea vs Ari |
| 48 | Odell Beckham | Cle vs Bal |
| 49 | Mike Boone | Min vs GB |
| 50 | David Montgomery (GTD) | Chi vs KC |
| 51 | Sterling Shepard | NYG @ Wsh |
| 52 | Mike Williams | LAC vs Oak |
| 53 | Anthony Miller | Chi vs KC |
| 54 | Adrian Peterson | Wsh vs NYG |
| 55 | Jamison Crowder | NYJ vs Pit |
| 56 | Christian Kirk | Ari @ Sea |
| 57 | Robby Anderson (GTD) | NYJ vs Pit |
| 58 | Darius Slayton | NYG @ Wsh |
| 59 | Hunter Henry | LAC vs Oak |
| 60 | Patrick Laird | Mia vs Cin |
| 61 | Greg Ward | Phi vs Dal |
| 62 | Kareem Hunt | Cle vs Bal |
| 63 | Tyrell Williams | Oak @ LAC |
| 64 | Jack Doyle | Ind vs Car |
| 65 | Marquise Brown | Bal @ Cle |
| 66 | Dede Westbrook | Jax @ Atl |
| 67 | Danny Amendola | Det @ Den |
| 68 | Jared Cook | NO @ Ten |
| 69 | Dion Lewis | Ten vs NO |
| 70 | Tarik Cohen | Chi vs KC |
