All position rankings are: QB | RB | WR | TE | FLEX | D
These rankings were updated as of Sun 10:42 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | Car @ Ind |
| 2 | Saquon Barkley | NYG @ Wsh |
| 3 | Ezekiel Elliott | Dal @ Phi |
| 4 | Leonard Fournette | Jax @ Atl |
| 5 | Chris Carson | Sea vs Ari |
| 6 | Alvin Kamara | NO @ Ten |
| 7 | Joe Mixon | Cin @ Mia |
| 8 | Melvin Gordon | LAC vs Oak |
| 9 | Le'Veon Bell | NYJ vs Pit |
| 10 | Aaron Jones | GB @ Min |
| 11 | Devonta Freeman | Atl vs Jax |
| 12 | James Conner | Pit @ NYJ |
| 13 | Kenyan Drake | Ari @ Sea |
| 14 | Miles Sanders | Phi vs Dal |
| 15 | Nick Chubb | Cle vs Bal |
| 16 | Austin Ekeler | LAC vs Oak |
| 17 | Mark Ingram | Bal @ Cle |
| 18 | Marlon Mack | Ind vs Car |
| 19 | Phillip Lindsay | Den vs Det |
| 20 | DeAndre Washington | Oak @ LAC |
| Rank | Player | Match |
| 21 | Mike Boone | Min vs GB |
| 22 | David Montgomery (GTD) | Chi vs KC |
| 23 | Adrian Peterson | Wsh vs NYG |
| 24 | Patrick Laird | Mia vs Cin |
| 25 | Kareem Hunt | Cle vs Bal |
| 26 | Dion Lewis | Ten vs NO |
| 27 | Tarik Cohen | Chi vs KC |
| 28 | Kerryon Johnson | Det @ Den |
| 29 | Jalen Richard | Oak @ LAC |
| 30 | Jamaal Williams | GB @ Min |
| 31 | Royce Freeman | Den vs Det |
| 32 | Boston Scott | Phi vs Dal |
| 33 | Latavius Murray | NO @ Ten |
| 34 | Derrick Henry (GTD) | Ten vs NO |
| 35 | Nyheim Hines | Ind vs Car |
| 36 | Myles Gaskin | Mia vs Cin |
| 37 | Alexander Mattison (que) | Min vs GB |
| 38 | Chris Thompson | Wsh vs NYG |
| 39 | Damien Williams | KC @ Chi |
| 40 | LeSean McCoy | KC @ Chi |
