All position rankings are: QB | RB | WR | TE | FLEX | D
These rankings were updated as of Sat 12:19 PM ET.
| Rank | Player | Match |
| 1 | Lamar Jackson | Bal vs Hou |
| 2 | Patrick Mahomes | KC vs LAC |
| 3 | Deshaun Watson | Hou @ Bal |
| 4 | Dak Prescott | Dal @ Det |
| 5 | Drew Brees | NO @ TB |
| 6 | Josh Allen | Buf @ Mia |
| 7 | Jameis Winston | TB vs NO |
| 8 | Matt Ryan | Atl @ Car |
| 9 | Tom Brady | NE @ Phi |
| 10 | Derek Carr | Oak vs Cin |
| 11 | Philip Rivers | LAC @ KC |
| 12 | Kyle Allen | Car vs Atl |
| 13 | Jimmy Garoppolo | SF vs Ari |
| 14 | Kirk Cousins | Min vs Den |
| 15 | Jared Goff | LAR vs Chi |
| 16 | Kyler Murray | Ari @ SF |
| 17 | Carson Wentz | Phi vs NE |
| 18 | Jacoby Brissett | Ind vs Jax |
| 19 | Nick Foles | Jax @ Ind |
| 20 | Ryan Fitzpatrick | Mia vs Buf |
| 21 | Jeff Driskel | Det vs Dal |
| 22 | Sam Darnold | NYJ @ Wsh |
| 23 | Mitchell Trubisky | Chi @ LAR |
| 24 | Ryan Finley | Cin @ Oak |
| 25 | Dwayne Haskins Jr. | Wsh vs NYJ |
