All position rankings are: QB | RB | WR | TE | FLEX | D
These rankings were updated as of Sat 10:36 AM ET.
| Rank | Player | Match |
| 1 | Michael Thomas | NO vs Ari |
| 2 | DeAndre Hopkins | Hou vs Oak |
| 3 | Tyler Lockett | Sea @ Atl |
| 4 | Julio Jones | Atl vs Sea |
| 5 | Cooper Kupp | LAR @ Cin |
| 6 | Kenny Golladay | Det vs NYG |
| 7 | Chris Godwin | TB @ Ten |
| 8 | Julian Edelman (que) | NE vs Cle |
| 9 | Mike Evans | TB @ Ten |
| 10 | T.Y. Hilton | Ind vs Den |
| 11 | Odell Beckham | Cle @ NE |
| 12 | Tyreek Hill | KC vs GB |
| 13 | Courtland Sutton | Den @ Ind |
| 14 | Allen Robinson | Chi vs LAC |
| 15 | Tyler Boyd | Cin vs LAR |
| 16 | JuJu Smith-Schuster | Pit vs Mia |
| 17 | Robert Woods | LAR @ Cin |
| 18 | Marvin Jones | Det vs NYG |
| 19 | John Brown | Buf vs Phi |
| 20 | D.J. Chark | Jax vs NYJ |
| 21 | Keenan Allen (que) | LAC @ Chi |
| 22 | Alshon Jeffery | Phi @ Buf |
| 23 | Marquez Valdes-Scantling (GTD) | GB @ KC |
| 24 | Calvin Ridley | Atl vs Sea |
| 25 | Brandin Cooks | LAR @ Cin |
| Rank | Player | Match |
| 26 | Larry Fitzgerald | Ari @ NO |
| 27 | Golden Tate | NYG @ Det |
| 28 | D.J. Moore | Car @ SF |
| 29 | Kenny Stills | Hou vs Oak |
| 30 | D.K. Metcalf | Sea @ Atl |
| 31 | Curtis Samuel | Car @ SF |
| 32 | Dede Westbrook (que) | Jax vs NYJ |
| 33 | Tyrell Williams (que) | Oak @ Hou |
| 34 | Jamison Crowder (GTD) | NYJ @ Jax |
| 35 | Mike Williams | LAC @ Chi |
| 36 | Jarvis Landry | Cle @ NE |
| 37 | Corey Davis | Ten vs TB |
| 38 | Robby Anderson | NYJ @ Jax |
| 39 | Cole Beasley | Buf vs Phi |
| 40 | Preston Williams | Mia @ Pit |
| 41 | Keke Coutee | Hou vs Oak |
| 42 | Auden Tate | Cin vs LAR |
| 43 | Geronimo Allison | GB @ KC |
| 44 | DeVante Parker | Mia @ Pit |
| 45 | Christian Kirk (que) | Ari @ NO |
| 46 | Phillip Dorsett | NE vs Cle |
| 47 | Danny Amendola | Det vs NYG |
| 48 | A.J. Brown | Ten vs TB |
| 49 | Sammy Watkins | KC vs GB |
| 50 | Diontae Johnson | Pit vs Mia |
