All position rankings are: QB | RB | WR | TE | FLEX | D
These rankings were updated as of Sun 9:47 AM ET.
| Rank | Player | Match |
| 1 | Patrick Mahomes | KC @ Det |
| 2 | Deshaun Watson | Hou vs Car |
| 3 | Lamar Jackson | Bal vs Cle |
| 4 | Russell Wilson | Sea @ Ari |
| 5 | Dak Prescott | Dal @ NO |
| 6 | Jared Goff | LAR vs TB |
| 7 | Philip Rivers | LAC @ Mia |
| 8 | Matt Ryan | Atl vs Ten |
| 9 | Daniel Jones | NYG vs Wsh |
| 10 | Kyler Murray | Ari vs Sea |
| 11 | Jameis Winston | TB @ LAR |
| 12 | Tom Brady | NE @ Buf |
| 13 | Matthew Stafford (que) | Det vs KC |
| 14 | Mason Rudolph | Pit vs Cin |
| 15 | Baker Mayfield | Cle @ Bal |
| 16 | Josh Allen | Buf vs NE |
| 17 | Case Keenum | Wsh @ NYG |
| 18 | Jacoby Brissett | Ind vs Oak |
| 19 | Kyle Allen | Car @ Hou |
| 20 | Marcus Mariota | Ten @ Atl |
| 21 | Andy Dalton | Cin @ Pit |
| 22 | Mitchell Trubisky | Chi vs Min |
| 23 | Derek Carr | Oak @ Ind |
| 24 | Gardner Minshew | Jax @ Den |
| 25 | Kirk Cousins | Min @ Chi |
