All position rankings are: QB | RB | WR | TE | FLEX | D
These rankings were updated as of Sun 9:47 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | Car @ Hou |
| 2 | Austin Ekeler | LAC @ Mia |
| 3 | Alvin Kamara | NO vs Dal |
| 4 | Ezekiel Elliott | Dal @ NO |
| 5 | Keenan Allen | LAC @ Mia |
| 6 | Dalvin Cook | Min @ Chi |
| 7 | James Conner | Pit vs Cin |
| 8 | DeAndre Hopkins | Hou vs Car |
| 9 | David Johnson | Ari vs Sea |
| 10 | Julio Jones | Atl vs Ten |
| 11 | Leonard Fournette | Jax @ Den |
| 12 | Nick Chubb | Cle @ Bal |
| 13 | Travis Kelce | KC @ Det |
| 14 | Odell Beckham | Cle @ Bal |
| 15 | Marlon Mack | Ind vs Oak |
| 16 | Chris Carson | Sea @ Ari |
| 17 | Sammy Watkins | KC @ Det |
| 18 | Todd Gurley | LAR vs TB |
| 19 | Amari Cooper | Dal @ NO |
| 20 | Michael Thomas | NO vs Dal |
| 21 | Kerryon Johnson | Det vs KC |
| 22 | Tyler Lockett | Sea @ Ari |
| 23 | JuJu Smith-Schuster | Pit vs Cin |
| 24 | Mike Evans | TB @ LAR |
| 25 | Derrick Henry | Ten @ Atl |
| 26 | Kenny Golladay | Det vs KC |
| 27 | Brandin Cooks | LAR vs TB |
| 28 | Cooper Kupp | LAR vs TB |
| 29 | Mark Ingram | Bal vs Cle |
| 30 | Chris Godwin (que) | TB @ LAR |
| 31 | Devonta Freeman | Atl vs Ten |
| 32 | Phillip Lindsay | Den vs Jax |
| 33 | Evan Engram | NYG vs Wsh |
| 34 | Sterling Shepard | NYG vs Wsh |
| 35 | Joe Mixon | Cin @ Pit |
| Rank | Player | Match |
| 36 | Tyler Boyd | Cin @ Pit |
| 37 | Robert Woods | LAR vs TB |
| 38 | Julian Edelman (que) | NE @ Buf |
| 39 | Adam Thielen | Min @ Chi |
| 40 | Christian Kirk | Ari vs Sea |
| 41 | Wayne Gallman | NYG vs Wsh |
| 42 | Larry Fitzgerald | Ari vs Sea |
| 43 | Marquise Brown | Bal vs Cle |
| 44 | Terry McLaurin (que) | Wsh @ NYG |
| 45 | Josh Jacobs | Oak @ Ind |
| 46 | Josh Gordon | NE @ Buf |
| 47 | Allen Robinson | Chi vs Min |
| 48 | David Montgomery | Chi vs Min |
| 49 | LeSean McCoy (GTD) | KC @ Det |
| 50 | D.J. Moore | Car @ Hou |
| 51 | Sony Michel | NE @ Buf |
| 52 | Darren Waller | Oak @ Ind |
| 53 | Chris Thompson | Wsh @ NYG |
| 54 | Calvin Ridley (GTD) | Atl vs Ten |
| 55 | Curtis Samuel | Car @ Hou |
| 56 | Marvin Jones | Det vs KC |
| 57 | Demarcus Robinson | KC @ Det |
| 58 | Kenyan Drake | Mia vs LAC |
| 59 | Tyrell Williams | Oak @ Ind |
| 60 | Mecole Hardman | KC @ Det |
| 61 | Carlos Hyde | Hou vs Car |
| 62 | Will Fuller | Hou vs Car |
| 63 | James White (GTD) | NE @ Buf |
| 64 | Emmanuel Sanders | Den vs Jax |
| 65 | Stefon Diggs | Min @ Chi |
| 66 | Mark Andrews (que) | Bal vs Cle |
| 67 | Jarvis Landry | Cle @ Bal |
| 68 | Courtland Sutton | Den vs Jax |
| 69 | D.K. Metcalf | Sea @ Ari |
| 70 | Adrian Peterson | Wsh @ NYG |
