All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 11:13 AM ET.
| Rank | Player | Match |
| 1 | Jahmyr Gibbs | Det vs NE |
| 2 | Christian McCaffrey | SF @ Dal |
| 3 | Bijan Robinson | Atl vs KC |
| 4 | Kenneth Walker (Q) | KC @ Atl |
| 5 | Jaxon Smith-Njigba | Sea @ LV |
| 6 | CeeDee Lamb | Dal vs SF |
| 7 | James Cook | Buf @ NYJ |
| 8 | Ja'Marr Chase | Cin vs Pit |
| 9 | Derrick Henry | Bal vs LAC |
| 10 | Chuba Hubbard | Car @ NO |
| 11 | Amon-Ra St. Brown (Q) | Det vs NE |
| 12 | Jonathan Taylor | Ind vs Mia |
| 13 | Kyren Williams | LAR @ Ari |
| 14 | Tee Higgins | Cin vs Pit |
| 15 | Jaylen Warren | Pit @ Cin |
| 16 | Bhayshul Tuten | Jax @ Ten |
| 17 | Javonte Williams | Dal vs SF |
| 18 | George Kittle | SF @ Dal |
| 19 | Chris Olave | NO vs Car |
| 20 | Parker Washington | Jax @ Ten |
| 21 | Christian Watson | GB vs Min |
| 22 | Justin Jefferson | Min @ GB |
| 23 | Ollie Gordon | Mia @ Ind |
| 24 | Chase Brown | Cin vs Pit |
| 25 | Matthew Golden | GB vs Min |
| 26 | Trey McBride | Ari vs LAR |
| 27 | Drake London | Atl vs KC |
| 28 | Breece Hall | NYJ vs Buf |
| 29 | Zay Flowers | Bal vs LAC |
| 30 | Zach Charbonnet | Sea @ LV |
| 31 | George Pickens | Dal vs SF |
| 32 | Brock Bowers | LV vs Sea |
| 33 | Tetairoa McMillan | Car @ NO |
| 34 | Jameson Williams | Det vs NE |
| 35 | Woody Marks | Hou @ Cle |
| Rank | Player | Match |
| 36 | Travis Etienne (IR) | NO vs Car |
| 37 | Nico Collins | Hou @ Cle |
| 38 | Garrett Wilson (Q) | NYJ vs Buf |
| 39 | Travis Kelce | KC @ Atl |
| 40 | Tyler Allgeier | Ari vs LAR |
| 41 | Rashee Rice | KC @ Atl |
| 42 | D.K. Metcalf | Pit @ Cin |
| 43 | Tony Pollard | Ten vs Jax |
| 44 | Tyler Warren | Ind vs Mia |
| 45 | D.J. Moore | Buf @ NYJ |
| 46 | Wan'Dale Robinson | Ten vs Jax |
| 47 | Quinshon Judkins | Cle vs Hou |
| 48 | Corey Kiner | NE @ Det |
| 49 | NO vs Car | |
| 50 | Sam LaPorta | Det vs NE |
| 51 | Khalil Shakir | Buf @ NYJ |
| 52 | Blake Corum | LAR @ Ari |
| 53 | Dalton Kincaid | Buf @ NYJ |
| 54 | Demario Douglas | NE @ Det |
| 55 | Tucker Kraft | GB vs Min |
| 56 | Jakobi Meyers | Jax @ Ten |
| 57 | Brenton Strange | Jax @ Ten |
| 58 | Omarion Hampton | LAC @ Bal |
| 59 | Mike Washington | LV vs Sea |
| 60 | Jalen Coker | Car @ NO |
| 61 | Deebo Samuel | SF @ Dal |
| 62 | Germie Bernard | Pit @ Cin |
| 63 | Jadarian Price | Sea @ LV |
| 64 | Jordan Addison (Q) | Min @ GB |
| 65 | Braelon Allen | NYJ vs Buf |
| 66 | Jordan Mason | Min @ GB |
| 67 | Denzel Boston (Q) | Cle vs Hou |
| 68 | Rico Dowdle | Pit @ Cin |
| 69 | Alvin Kamara | NO vs Car |
| 70 | Caleb Douglas | Mia @ Ind |
