All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 12:53 PM ET.
| Rank | Player | Match |
| 1 | Bijan Robinson | Atl vs Chi |
| 2 | Jonathan Taylor | Ind vs Ten |
| 3 | Kenneth Walker III | KC vs LAC |
| 4 | Christian McCaffrey | SF vs Wsh |
| 5 | Kyren Williams | LAR vs Ari |
| 6 | Derrick Henry | Bal @ Cle |
| 7 | James Cook | Buf @ LV |
| 8 | Chuba Hubbard | Car @ Phi |
| 9 | Jaylen Warren | Pit @ TB |
| 10 | Javonte Williams | Dal @ GB |
| 11 | Ashton Jeanty | LV vs Buf |
| 12 | Rhamondre Stevenson | NE vs NYJ |
| 13 | D'Andre Swift | Chi @ Atl |
| 14 | Bucky Irving | TB vs Pit |
| 15 | Cam Skattebo | NYG vs NO |
| 16 | Bhayshul Tuten | Jax vs Hou |
| 17 | Woody Marks | Hou @ Jax |
| 18 | Tony Pollard | Ten @ Ind |
| 19 | MarShawn Lloyd | GB vs Dal |
| 20 | Braelon Allen | NYJ @ NE |
| Rank | Player | Match |
| 21 | Dameon Pierce | Phi vs Car |
| 22 | Alvin Kamara (Q) | NO @ NYG |
| 23 | Quinshon Judkins (Q) | Cle vs Bal |
| 24 | Tyler Allgeier | Ari @ LAR |
| 25 | Jacory Croskey-Merritt (Q) | Wsh @ SF |
| 26 | Blake Corum | LAR vs Ari |
| 27 | Omarion Hampton | LAC @ KC |
| 28 | Brian Robinson | Atl vs Chi |
| 29 | Kendre Miller | NO @ NYG |
| 30 | Breece Hall (Out) | NYJ @ NE |
| 31 | Keaton Mitchell | LAC @ KC |
| 32 | Rico Dowdle (Q) | Pit @ TB |
| 33 | Tyjae Spears (Q) | Ten @ Ind |
| 34 | Kaleb Johnson | GB vs Dal |
| 35 | Kenneth Gainwell | TB vs Pit |
| 36 | Rachaad White (Q) | Wsh @ SF |
| 37 | Kimani Vidal | LAC @ KC |
| 38 | Ty Johnson | Buf @ LV |
| 39 | Kaelon Black | SF vs Wsh |
| 40 | Pierre Strong Jr. | GB vs Dal |
