All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 12:03 PM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF @ Ari |
| 2 | De'Von Achane | Mia vs Wsh |
| 3 | Bijan Robinson | Atl vs Car |
| 4 | Josh Jacobs | GB @ NYG |
| 5 | James Cook | Buf vs TB |
| 6 | Jahmyr Gibbs | Det @ Phi |
| 7 | Saquon Barkley | Phi vs Det |
| 8 | Ashton Jeanty | LV vs Dal |
| 9 | TreVeyon Henderson | NE vs NYJ |
| 10 | Rico Dowdle (Q) | Car @ Atl |
| 11 | Jaylen Warren | Pit vs Cin |
| 12 | Travis Etienne | Jax vs LAC |
| 13 | Javonte Williams | Dal @ LV |
| 14 | Derrick Henry | Bal @ Cle |
| 15 | Kyren Williams | LAR vs Sea |
| 16 | Chase Brown | Cin @ Pit |
| 17 | Breece Hall | NYJ @ NE |
| 18 | Kimani Vidal | LAC @ Jax |
| 19 | Quinshon Judkins | Cle vs Bal |
| 20 | Woody Marks | Hou @ Ten |
| Rank | Player | Match |
| 21 | Rachaad White | TB @ Buf |
| 22 | D'Andre Swift (Q) | Chi @ Min |
| 23 | Jacory Croskey-Merritt | Wsh @ Mia |
| 24 | RJ Harvey | Den vs KC |
| 25 | Aaron Jones (Q) | Min vs Chi |
| 26 | Kenneth Walker III | Sea @ LAR |
| 27 | Tyrone Tracy Jr. | NYG vs GB |
| 28 | David Montgomery | Det @ Phi |
| 29 | Kareem Hunt | KC @ Den |
| 30 | Jordan Mason | Min vs Chi |
| 31 | Tyjae Spears | Ten vs Hou |
| 32 | Tony Pollard | Ten vs Hou |
| 33 | Zach Charbonnet | Sea @ LAR |
| 34 | Kenneth Gainwell | Pit vs Cin |
| 35 | Emari Demercado | Ari vs SF |
| 36 | Nick Chubb | Hou @ Ten |
| 37 | Tyler Allgeier | Atl vs Car |
| 38 | Kyle Monangai | Chi @ Min |
| 39 | Sean Tucker | TB @ Buf |
| 40 | Trey Benson (IR) | Ari vs SF |
