All position ranks are: QB RB WR TE DEF
These rankings were updated as of Sat 1:39 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Ari |
| 2 | Bijan Robinson | Atl @ Car |
| 3 | Saquon Barkley | Phi vs LAR |
| 4 | Jonathan Taylor | Ind @ Ten |
| 5 | CeeDee Lamb | Dal @ Chi |
| 6 | Derrick Henry | Bal vs Det |
| 7 | Jahmyr Gibbs | Det @ Bal |
| 8 | Josh Jacobs | GB @ Cle |
| 9 | Malik Nabers | NYG vs KC |
| 10 | Ja'Marr Chase | Cin @ Min |
| 11 | Justin Jefferson | Min vs Cin |
| 12 | Bucky Irving | TB vs NYJ |
| 13 | Puka Nacua | LAR @ Phi |
| 14 | Chase Brown | Cin @ Min |
| 15 | Amon-Ra St. Brown | Det @ Bal |
| 16 | Javonte Williams | Dal @ Chi |
| 17 | Kyren Williams | LAR @ Phi |
| 18 | Nico Collins | Hou @ Jax |
| 19 | Chuba Hubbard | Car vs Atl |
| 20 | Jaxon Smith-Njigba | Sea vs NO |
| 21 | Mike Evans | TB vs NYJ |
| 22 | Tony Pollard | Ten vs Ind |
| 23 | Jordan Mason | Min vs Cin |
| 24 | Breece Hall | NYJ @ TB |
| 25 | Jaylen Warren | Pit @ NE |
| 26 | James Conner | Ari vs Sea |
| 27 | Zay Flowers | Bal vs Det |
| 28 | Drake London | Atl @ Car |
| 29 | Ashton Jeanty | LV @ Wsh |
| 30 | Brian Thomas Jr. | Jax vs Hou |
| 31 | Alvin Kamara | NO @ Sea |
| 32 | Davante Adams | LAR @ Phi |
| 33 | Kenneth Walker III | Sea vs NO |
| 34 | D.K. Metcalf | Pit @ NE |
| 35 | Rome Odunze | Chi vs Dal |
| Rank | Player | Match |
| 36 | Garrett Wilson | NYJ @ TB |
| 37 | Ladd McConkey | LAC vs Den |
| 38 | Trey McBride | Ari vs Sea |
| 39 | J.K. Dobbins | Den @ LAC |
| 40 | Deebo Samuel | Wsh vs LV |
| 41 | Terry McLaurin | Wsh vs LV |
| 42 | D'Andre Swift (Q) | Chi vs Dal |
| 43 | Emeka Egbuka (Q) | TB vs NYJ |
| 44 | A.J. Brown | Phi vs LAR |
| 45 | Nick Chubb | Hou @ Jax |
| 46 | Brock Bowers | LV @ Wsh |
| 47 | Jakobi Meyers | LV @ Wsh |
| 48 | Jacory Croskey-Merritt | Wsh vs LV |
| 49 | Travis Etienne | Jax vs Hou |
| 50 | George Pickens | Dal @ Chi |
| 51 | Tee Higgins | Cin @ Min |
| 52 | Michael Pittman Jr. | Ind @ Ten |
| 53 | DeVonta Smith | Phi vs LAR |
| 54 | DJ Moore | Chi vs Dal |
| 55 | Courtland Sutton | Den @ LAC |
| 56 | Rhamondre Stevenson | NE vs Pit |
| 57 | Tetairoa McMillan | Car vs Atl |
| 58 | Marvin Harrison Jr. | Ari vs Sea |
| 59 | David Montgomery | Det @ Bal |
| 60 | Ricky Pearsall | SF vs Ari |
| 61 | Jauan Jennings (Q) | SF vs Ari |
| 62 | Keenan Allen | LAC vs Den |
| 63 | Chris Olave | NO @ Sea |
| 64 | Tucker Kraft (Q) | GB @ Cle |
| 65 | Tyler Warren (Q) | Ind @ Ten |
| 66 | Jerry Jeudy | Cle vs GB |
| 67 | Calvin Ridley | Ten vs Ind |
| 68 | Jameson Williams | Det @ Bal |
| 69 | Zach Charbonnet (D) | Sea vs NO |
| 70 | Omarion Hampton | LAC vs Den |
