All position ranks are: QB WR TE FLEX DEF
These rankings were updated as of Sat 1:39 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Ari |
| 2 | Bijan Robinson | Atl @ Car |
| 3 | Saquon Barkley | Phi vs LAR |
| 4 | Jonathan Taylor | Ind @ Ten |
| 5 | Derrick Henry | Bal vs Det |
| 6 | Jahmyr Gibbs | Det @ Bal |
| 7 | Josh Jacobs | GB @ Cle |
| 8 | Bucky Irving | TB vs NYJ |
| 9 | Chase Brown | Cin @ Min |
| 10 | Javonte Williams | Dal @ Chi |
| 11 | Kyren Williams | LAR @ Phi |
| 12 | Chuba Hubbard | Car vs Atl |
| 13 | Tony Pollard | Ten vs Ind |
| 14 | Jordan Mason | Min vs Cin |
| 15 | Breece Hall | NYJ @ TB |
| 16 | Jaylen Warren | Pit @ NE |
| 17 | James Conner | Ari vs Sea |
| 18 | Ashton Jeanty | LV @ Wsh |
| 19 | Alvin Kamara | NO @ Sea |
| 20 | Kenneth Walker III | Sea vs NO |
| Rank | Player | Match |
| 21 | J.K. Dobbins | Den @ LAC |
| 22 | D'Andre Swift (Q) | Chi vs Dal |
| 23 | Nick Chubb | Hou @ Jax |
| 24 | Jacory Croskey-Merritt | Wsh vs LV |
| 25 | Travis Etienne | Jax vs Hou |
| 26 | Rhamondre Stevenson | NE vs Pit |
| 27 | David Montgomery | Det @ Bal |
| 28 | Zach Charbonnet (D) | Sea vs NO |
| 29 | Omarion Hampton | LAC vs Den |
| 30 | Cam Skattebo | NYG vs KC |
| 31 | Quinshon Judkins | Cle vs GB |
| 32 | Tyrone Tracy Jr. | NYG vs KC |
| 33 | Kareem Hunt | KC @ NYG |
| 34 | TreVeyon Henderson | NE vs Pit |
| 35 | Isiah Pacheco | KC @ NYG |
| 36 | Rachaad White | TB vs NYJ |
| 37 | Bhayshul Tuten | Jax vs Hou |
| 38 | Trey Benson | Ari vs Sea |
| 39 | Tyler Allgeier | Atl @ Car |
| 40 | RJ Harvey | Den @ LAC |
