All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 9:14 AM ET.
| Rank | Player | Match |
| 1 | CeeDee Lamb | Dal @ Atl |
| 2 | Ja'Marr Chase | Cin vs LV |
| 3 | Alvin Kamara | NO @ Car |
| 4 | Kyren Williams | LAR @ Sea |
| 5 | Justin Jefferson | Min vs Ind |
| 6 | Saquon Barkley | Phi vs Jax |
| 7 | Bijan Robinson | Atl vs Dal |
| 8 | Derrick Henry | Bal vs Den |
| 9 | Aaron Jones | Min vs Ind |
| 10 | Jahmyr Gibbs | Det @ GB |
| 11 | A.J. Brown | Phi vs Jax |
| 12 | Kenneth Walker III | Sea vs LAR |
| 13 | Jonathan Taylor | Ind @ Min |
| 14 | De'Von Achane | Mia @ Buf |
| 15 | Kareem Hunt (P) | KC vs TB |
| 16 | Drake London | Atl vs Dal |
| 17 | Amon-Ra St. Brown | Det @ GB |
| 18 | J.K. Dobbins | LAC @ Cle |
| 19 | Tony Pollard (Q) | Ten vs NE |
| 20 | Tyreek Hill | Mia @ Buf |
| 21 | Chase Brown | Cin vs LV |
| 22 | D'Andre Swift | Chi @ Ari |
| 23 | Malik Nabers | NYG vs Wsh |
| 24 | James Conner | Ari vs Chi |
| 25 | James Cook | Buf vs Mia |
| 26 | Josh Jacobs (Q) | GB vs Det |
| 27 | Puka Nacua (Q) | LAR @ Sea |
| 28 | Cooper Kupp | LAR @ Sea |
| 29 | Chuba Hubbard | Car vs NO |
| 30 | Chris Olave | NO @ Car |
| 31 | Terry McLaurin | Wsh @ NYG |
| 32 | Travis Kelce | KC vs TB |
| 33 | DeVonta Smith | Phi vs Jax |
| 34 | David Montgomery | Det @ GB |
| 35 | Nick Chubb | Cle vs LAC |
| Rank | Player | Match |
| 36 | Alexander Mattison | LV @ Cin |
| 37 | DJ Moore | Chi @ Ari |
| 38 | Rhamondre Stevenson | NE @ Ten |
| 39 | Brock Bowers | LV @ Cin |
| 40 | Tyrone Tracy Jr. | NYG vs Wsh |
| 41 | Brian Robinson (Q) | Wsh @ NYG |
| 42 | Josh Downs | Ind @ Min |
| 43 | Darnell Mooney | Atl vs Dal |
| 44 | Zay Flowers | Bal vs Den |
| 45 | Jaxon Smith-Njigba | Sea vs LAR |
| 46 | Marvin Harrison Jr. | Ari vs Chi |
| 47 | Jayden Reed | GB vs Det |
| 48 | Trey McBride | Ari vs Chi |
| 49 | Jakobi Meyers | LV @ Cin |
| 50 | Javonte Williams | Den @ Bal |
| 51 | Tyler Lockett | Sea vs LAR |
| 52 | Rico Dowdle | Dal @ Atl |
| 53 | Tank Bigsby (Q) | Jax @ Phi |
| 54 | Courtland Sutton | Den @ Bal |
| 55 | Ladd McConkey | LAC @ Cle |
| 56 | David Njoku | Cle vs LAC |
| 57 | Calvin Ridley | Ten vs NE |
| 58 | Michael Pittman | Ind @ Min |
| 59 | Amari Cooper (Q) | Buf vs Mia |
| 60 | Khalil Shakir | Buf vs Mia |
| 61 | Jaylen Waddle | Mia @ Buf |
| 62 | Evan Engram | Jax @ Phi |
| 63 | Kyle Pitts | Atl vs Dal |
| 64 | Xavier Worthy | KC vs TB |
| 65 | Rachaad White | TB @ KC |
| 66 | Keenan Allen | Chi @ Ari |
| 67 | Cedric Tillman | Cle vs LAC |
| 68 | Keon Coleman | Buf vs Mia |
| 69 | DeAndre Hopkins | KC vs TB |
| 70 | Cade Otton | TB @ KC |
