All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 9:47 AM ET.
| Rank | Player | Match |
| 1 | Kyren Williams | LAR vs GB |
| 2 | Derrick Henry | Bal @ Cin |
| 3 | CeeDee Lamb | Dal @ Pit |
| 4 | Jordan Mason | SF vs Ari |
| 5 | Alvin Kamara (Q) | NO @ KC |
| 6 | Nico Collins | Hou vs Buf |
| 7 | Ja'Marr Chase | Cin vs Bal |
| 8 | Kenneth Walker III | Sea vs NYG |
| 9 | Deebo Samuel Sr. | SF vs Ari |
| 10 | Jayden Reed | GB @ LAR |
| 11 | De'Von Achane | Mia @ NE |
| 12 | Chuba Hubbard | Car @ Chi |
| 13 | Najee Harris | Pit vs Dal |
| 14 | Josh Jacobs | GB @ LAR |
| 15 | DK Metcalf | Sea vs NYG |
| 16 | Marvin Harrison Jr. | Ari @ SF |
| 17 | James Conner | Ari @ SF |
| 18 | Brian Robinson Jr. (Q) | Wsh vs Cle |
| 19 | James Cook | Buf @ Hou |
| 20 | Travis Etienne Jr. | Jax vs Ind |
| 21 | Tyreek Hill | Mia @ NE |
| 22 | Diontae Johnson | Car @ Chi |
| 23 | DJ Moore | Chi vs Car |
| 24 | Stefon Diggs | Hou vs Buf |
| 25 | Brandon Aiyuk | SF vs Ari |
| 26 | George Pickens | Pit vs Dal |
| 27 | Travis Kelce | KC vs NO |
| 28 | George Kittle (Q) | SF vs Ari |
| 29 | Terry McLaurin | Wsh vs Cle |
| 30 | Wan'Dale Robinson | NYG @ Sea |
| 31 | Zack Moss | Cin vs Bal |
| 32 | Jerome Ford | Cle @ Wsh |
| 33 | Chris Olave | NO @ KC |
| 34 | Amari Cooper | Cle @ Wsh |
| 35 | Christian Kirk | Jax vs Ind |
| Rank | Player | Match |
| 36 | D'Andre Swift | Chi vs Car |
| 37 | Michael Pittman Jr. | Ind @ Jax |
| 38 | Zay Flowers | Bal @ Cin |
| 39 | Rhamondre Stevenson | NE vs Mia |
| 40 | Brian Thomas Jr. | Jax vs Ind |
| 41 | Dontayvion Wicks | GB @ LAR |
| 42 | Tee Higgins | Cin vs Bal |
| 43 | Trey McBride | Ari @ SF |
| 44 | Rashid Shaheed | NO @ KC |
| 45 | Javonte Williams | Den vs LV |
| 46 | Tank Dell | Hou vs Buf |
| 47 | Jakobi Meyers | LV @ Den |
| 48 | Alexander Mattison | LV @ Den |
| 49 | Courtland Sutton | Den vs LV |
| 50 | Keenan Allen | Chi vs Car |
| 51 | Xavier Worthy | KC vs NO |
| 52 | Tyrone Tracy Jr. | NYG @ Sea |
| 53 | Jauan Jennings | SF vs Ari |
| 54 | Brock Bowers | LV @ Den |
| 55 | Jaxon Smith-Njigba | Sea vs NYG |
| 56 | Rico Dowdle | Dal @ Pit |
| 57 | Jerry Jeudy | Cle @ Wsh |
| 58 | Jake Ferguson | Dal @ Pit |
| 59 | Dalton Kincaid | Buf @ Hou |
| 60 | Cam Akers | Hou vs Buf |
| 61 | Jaylen Waddle | Mia @ NE |
| 62 | Josh Downs | Ind @ Jax |
| 63 | Tutu Atwell | LAR vs GB |
| 64 | Tyler Lockett | Sea vs NYG |
| 65 | Xavier Legette | Car @ Chi |
| 66 | Tre Tucker | LV @ Den |
| 67 | Austin Ekeler | Wsh vs Cle |
| 68 | Rome Odunze | Chi vs Car |
| 69 | Demarcus Robinson | LAR vs GB |
| 70 | Darius Slayton | NYG @ Sea |
