All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 9:43 AM ET.
| Rank | Player | Match |
| 1 | Breece Hall | NYJ vs Den |
| 2 | Saquon Barkley | Phi @ TB |
| 3 | Bijan Robinson | Atl vs NO |
| 4 | De'Von Achane | Mia vs Ten |
| 5 | Alvin Kamara (Q) | NO @ Atl |
| 6 | Jahmyr Gibbs | Det vs Sea |
| 7 | Kyren Williams | LAR @ Chi |
| 8 | Jordan Mason | SF vs NE |
| 9 | Jonathan Taylor | Ind vs Pit |
| 10 | Derrick Henry | Bal vs Buf |
| 11 | James Conner | Ari vs Wsh |
| 12 | Aaron Jones | Min @ GB |
| 13 | Brian Robinson Jr. | Wsh @ Ari |
| 14 | Chuba Hubbard | Car vs Cin |
| 15 | James Cook | Buf @ Bal |
| 16 | Travis Etienne Jr. | Jax @ Hou |
| 17 | Josh Jacobs | GB vs Min |
| 18 | J.K. Dobbins | LAC vs KC |
| 19 | David Montgomery | Det vs Sea |
| 20 | Zack Moss | Cin @ Car |
| Rank | Player | Match |
| 21 | Najee Harris | Pit @ Ind |
| 22 | Rhamondre Stevenson | NE @ SF |
| 23 | Rachaad White | TB vs Phi |
| 24 | Tony Pollard | Ten @ Mia |
| 25 | Zach Charbonnet | Sea @ Det |
| 26 | Jerome Ford | Cle @ LV |
| 27 | Cam Akers | Hou vs Jax |
| 28 | Carson Steele | KC @ LAC |
| 29 | Braelon Allen | NYJ vs Den |
| 30 | Javonte Williams | Den @ NYJ |
| 31 | Zamir White | LV vs Cle |
| 32 | D'Andre Swift | Chi vs LAR |
| 33 | Roschon Johnson | Chi vs LAR |
| 34 | Tyjae Spears | Ten @ Mia |
| 35 | Bucky Irving (Q) | TB vs Phi |
| 36 | Alexander Mattison | LV vs Cle |
| 37 | Chase Brown | Cin @ Car |
| 38 | Kenneth Walker III (Q) | Sea @ Det |
| 39 | Ty Chandler | Min @ GB |
| 40 | Samaje Perine | KC @ LAC |
