All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sat 12:21 PM ET.
| Rank | Player | Match |
| 1 | CeeDee Lamb | Dal vs NO |
| 2 | Cooper Kupp | LAR @ Ari |
| 3 | Bijan Robinson | Atl @ Phi |
| 4 | Breece Hall | NYJ vs NE |
| 5 | Saquon Barkley | Phi vs Atl |
| 6 | Kyren Williams | LAR @ Ari |
| 7 | Jonathan Taylor | Ind @ GB |
| 8 | Justin Jefferson | Min vs SF |
| 9 | Amon-Ra St. Brown | Det vs TB |
| 10 | A.J. Brown (Q) | Phi vs Atl |
| 11 | Deebo Samuel Sr. | SF @ Min |
| 12 | Joe Mixon | Hou vs Chi |
| 13 | Jahmyr Gibbs | Det vs TB |
| 14 | Ja'Marr Chase | Cin @ KC |
| 15 | Rashee Rice | KC vs Cin |
| 16 | Mike Evans | TB @ Det |
| 17 | Jordan Mason | SF @ Min |
| 18 | Rhamondre Stevenson | NE vs Sea |
| 19 | James Conner | Ari vs LAR |
| 20 | Derrick Henry | Bal vs LV |
| 21 | Isiah Pacheco | KC vs Cin |
| 22 | Garrett Wilson | NYJ vs NE |
| 23 | Alvin Kamara | NO @ Dal |
| 24 | Nico Collins | Hou vs Chi |
| 25 | Jerome Ford | Cle @ Jax |
| 26 | Rachaad White | TB @ Det |
| 27 | Josh Jacobs | GB vs Ind |
| 28 | DeVonta Smith | Phi vs Atl |
| 29 | Travis Kelce | KC vs Cin |
| 30 | Travis Etienne Jr. | Jax vs Cle |
| 31 | Michael Pittman | Ind @ GB |
| 32 | Chris Godwin | TB @ Det |
| 33 | Stefon Diggs | Hou vs Chi |
| 34 | Drake London | Atl @ Phi |
| 35 | J.K. Dobbins | LAC @ Car |
| Rank | Player | Match |
| 36 | Malik Nabers | NYG @ Wsh |
| 37 | Brandon Aiyuk | SF @ Min |
| 38 | Sam LaPorta | Det vs TB |
| 39 | Aaron Jones | Min vs SF |
| 40 | George Pickens | Pit @ Den |
| 41 | Brian Robinson Jr. | Wsh vs NYG |
| 42 | DJ Moore | Chi @ Hou |
| 43 | Zach Charbonnet | Sea @ NE |
| 44 | Davante Adams | LV @ Bal |
| 45 | David Montgomery | Det vs TB |
| 46 | Xavier Worthy | KC vs Cin |
| 47 | Tony Pollard | Ten vs NYJ |
| 48 | Tank Dell | Hou vs Chi |
| 49 | Amari Cooper | Cle @ Jax |
| 50 | Zay Flowers | Bal vs LV |
| 51 | Trey McBride | Ari vs LAR |
| 52 | Devin Singletary | NYG @ Wsh |
| 53 | Chris Olave | NO @ Dal |
| 54 | Najee Harris | Pit @ Den |
| 55 | Zack Moss | Cin @ KC |
| 56 | D'Andre Swift | Chi @ Hou |
| 57 | DK Metcalf | Sea @ NE |
| 58 | Christian Kirk | Jax vs Cle |
| 59 | George Kittle | SF @ Min |
| 60 | Jameson Williams (Q) | Det vs TB |
| 61 | Terry McLaurin | Wsh vs NYG |
| 62 | Marvin Harrison Jr. | Ari vs LAR |
| 63 | Ezekiel Elliott | Dal vs NO |
| 64 | Ladd McConkey | LAC @ Car |
| 65 | Keenan Allen (Q) | Chi @ Hou |
| 66 | Kyle Pitts | Atl @ Phi |
| 67 | Brian Thomas Jr. | Jax vs Cle |
| 68 | Jayden Reed (Q) | GB vs Ind |
| 69 | Brandin Cooks | Dal vs NO |
| 70 | Michael Pittman Jr. | Ind @ GB |
