All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 11:19 AM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF @ LAR |
| 2 | Tyreek Hill | Mia @ NE |
| 3 | Derrick Henry | Ten vs LAC |
| 4 | Stefon Diggs | Buf vs LV |
| 5 | Ja'Marr Chase | Cin vs Bal |
| 6 | Tony Pollard | Dal vs NYJ |
| 7 | Austin Ekeler (GTD) | LAC @ Ten |
| 8 | Saquon Barkley | NYG @ Ari |
| 9 | Justin Jefferson | Min @ Phi |
| 10 | Amon-Ra St. Brown | Det vs Sea |
| 11 | Nick Chubb | Cle @ Pit |
| 12 | Bijan Robinson | Atl vs GB |
| 13 | Davante Adams (GTD) | LV @ Buf |
| 14 | Calvin Ridley | Jax vs KC |
| 15 | A.J. Brown | Phi vs Min |
| 16 | Keenan Allen | LAC @ Ten |
| 17 | Josh Jacobs | LV @ Buf |
| 18 | Joe Mixon | Cin vs Bal |
| 19 | Jaylen Waddle (GTD) | Mia @ NE |
| 20 | Deebo Samuel | SF @ LAR |
| 21 | James Conner (GTD) | Ari vs NYG |
| 22 | CeeDee Lamb | Dal vs NYJ |
| 23 | D.K. Metcalf | Sea @ Det |
| 24 | Chris Olave | NO @ Car |
| 25 | Travis Etienne | Jax vs KC |
| 26 | David Montgomery | Det vs Sea |
| 27 | Rhamondre Stevenson | NE vs Mia |
| 28 | DeVonta Smith | Phi vs Min |
| 29 | DeAndre Hopkins (GTD) | Ten vs LAC |
| 30 | Kenneth Walker III | Sea @ Det |
| 31 | Tee Higgins | Cin vs Bal |
| 32 | Brandon Aiyuk | SF @ LAR |
| 33 | Travis Kelce | KC @ Jax |
| 34 | James Cook | Buf vs LV |
| 35 | Garrett Wilson | NYJ @ Dal |
| Rank | Player | Match |
| 36 | Jahmyr Gibbs | Det vs Sea |
| 37 | Mike Williams | LAC @ Ten |
| 38 | Mike Evans | TB vs Chi |
| 39 | Miles Sanders | Car vs NO |
| 40 | Tyler Lockett | Sea @ Det |
| 41 | Zay Flowers | Bal @ Cin |
| 42 | Dameon Pierce | Hou vs Ind |
| 43 | Chris Godwin | TB vs Chi |
| 44 | Rachaad White | TB vs Chi |
| 45 | Michael Pittman Jr. | Ind @ Hou |
| 46 | Tyler Allgeier | Atl vs GB |
| 47 | Brian Robinson | Wsh @ Den |
| 48 | Javonte Williams | Den vs Wsh |
| 49 | Najee Harris | Pit vs Cle |
| 50 | Alexander Mattison | Min @ Phi |
| 51 | Aaron Jones (GTD) | GB @ Atl |
| 52 | Amari Cooper | Cle @ Pit |
| 53 | Breece Hall (GTD) | NYJ @ Dal |
| 54 | Jamaal Williams | NO @ Car |
| 55 | George Pickens | Pit vs Cle |
| 56 | Puka Nacua | LAR vs SF |
| 57 | Christian Kirk | Jax vs KC |
| 58 | Gabriel Davis | Buf vs LV |
| 59 | Marquise Brown | Ari vs NYG |
| 60 | Terry McLaurin | Wsh @ Den |
| 61 | T.J. Hockenson | Min @ Phi |
| 62 | Nico Collins | Hou vs Ind |
| 63 | Brandin Cooks (GTD) | Dal vs NYJ |
| 64 | Raheem Mostert (GTD) | Mia @ NE |
| 65 | D.J. Moore | Chi @ TB |
| 66 | Isiah Pacheco | KC @ Jax |
| 67 | Courtland Sutton | Den vs Wsh |
| 68 | George Kittle | SF @ LAR |
| 69 | A.J. Dillon | GB @ Atl |
| 70 | Rashid Shaheed | NO @ Car |
