All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Thu 12:18 PM ET.
| Rank | Player | Match |
| 1 | Christian McCaffrey | SF vs Wsh |
| 2 | Tyreek Hill | Mia vs GB |
| 3 | Justin Jefferson | Min vs NYG |
| 4 | Austin Ekeler | LAC @ Ind |
| 5 | Derrick Henry | Ten vs Hou |
| 6 | Travis Kelce | KC vs Sea |
| 7 | Josh Jacobs | LV @ Pit |
| 8 | Saquon Barkley | NYG @ Min |
| 9 | Ja'Marr Chase | Cin @ NE |
| 10 | Dalvin Cook | Min vs NYG |
| 11 | Stefon Diggs | Buf @ Chi |
| 12 | Davante Adams | LV @ Pit |
| 13 | Amon-Ra St. Brown | Det @ Car |
| 14 | CeeDee Lamb | Dal vs Phi |
| 15 | A.J. Brown | Phi @ Dal |
| 16 | Alvin Kamara | NO @ Cle |
| 17 | James Conner | Ari vs TB |
| 18 | Jaylen Waddle | Mia vs GB |
| 19 | Nick Chubb (GTD) | Cle vs NO |
| 20 | D.K. Metcalf | Sea @ KC |
| 21 | Rhamondre Stevenson (GTD) | NE vs Cin |
| 22 | Aaron Jones | GB @ Mia |
| 23 | Tony Pollard | Dal vs Phi |
| 24 | Joe Mixon | Cin @ NE |
| 25 | DeAndre Hopkins | Ari vs TB |
| 26 | Keenan Allen | LAC @ Ind |
| 27 | Travis Etienne | Jax @ NYJ |
| 28 | Chris Godwin | TB @ Ari |
| 29 | Najee Harris | Pit vs LV |
| 30 | Mark Andrews | Bal vs Atl |
| 31 | Tee Higgins | Cin @ NE |
| 32 | David Montgomery | Chi vs Buf |
| 33 | J.K. Dobbins | Bal vs Atl |
| 34 | Kenneth Walker III | Sea @ KC |
| 35 | Miles Sanders | Phi @ Dal |
| Rank | Player | Match |
| 36 | Garrett Wilson | NYJ vs Jax |
| 37 | Christian Kirk | Jax @ NYJ |
| 38 | Jerick McKinnon | KC vs Sea |
| 39 | Mike Williams | LAC @ Ind |
| 40 | Michael Pittman Jr. | Ind vs LAC |
| 41 | Latavius Murray | Den @ LAR |
| 42 | Jerry Jeudy | Den @ LAR |
| 43 | Raheem Mostert | Mia vs GB |
| 44 | D.J. Moore | Car vs Det |
| 45 | Mike Evans | TB @ Ari |
| 46 | Terry McLaurin | Wsh @ SF |
| 47 | JuJu Smith-Schuster | KC vs Sea |
| 48 | Ezekiel Elliott | Dal vs Phi |
| 49 | Leonard Fournette | TB @ Ari |
| 50 | Christian Watson | GB @ Mia |
| 51 | D'Andre Swift | Det @ Car |
| 52 | DeVonta Smith | Phi @ Dal |
| 53 | Rachaad White | TB @ Ari |
| 54 | Diontae Johnson | Pit vs LV |
| 55 | Devin Singletary | Buf @ Chi |
| 56 | Jamaal Williams | Det @ Car |
| 57 | Brandon Aiyuk | SF vs Wsh |
| 58 | Isiah Pacheco | KC vs Sea |
| 59 | Adam Thielen | Min vs NYG |
| 60 | Gabriel Davis | Buf @ Chi |
| 61 | T.J. Hockenson | Min vs NYG |
| 62 | Amari Cooper | Cle vs NO |
| 63 | George Kittle | SF vs Wsh |
| 64 | Zay Jones (GTD) | Jax @ NYJ |
| 65 | Pat Freiermuth | Pit vs LV |
| 66 | D'Onta Foreman | Car vs Det |
| 67 | Allen Lazard | GB @ Mia |
| 68 | Darius Slayton | NYG @ Min |
| 69 | Dallas Goedert | Phi @ Dal |
| 70 | Marquise Brown | Ari vs TB |
