All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 10:39 AM ET.
| Rank | Player | Match |
| 1 | Derrick Henry | Ten @ LAC |
| 2 | Josh Jacobs (GTD) | LV vs NE |
| 3 | Austin Ekeler | LAC vs Ten |
| 4 | Alvin Kamara | NO vs Atl |
| 5 | James Conner | Ari @ Den |
| 6 | Saquon Barkley | NYG @ Wsh |
| 7 | Joe Mixon | Cin @ TB |
| 8 | Rhamondre Stevenson (GTD) | NE @ LV |
| 9 | Aaron Jones | GB vs LAR |
| 10 | Tony Pollard | Dal @ Jax |
| 11 | Miles Sanders | Phi @ Chi |
| 12 | David Montgomery | Chi vs Phi |
| 13 | Travis Etienne | Jax vs Dal |
| 14 | Zonovan Knight | NYJ vs Det |
| 15 | Latavius Murray | Den vs Ari |
| 16 | Najee Harris | Pit @ Car |
| 17 | Ezekiel Elliott | Dal @ Jax |
| 18 | Isiah Pacheco | KC @ Hou |
| 19 | Rachaad White | TB vs Cin |
| 20 | Brian Robinson | Wsh vs NYG |
| Rank | Player | Match |
| 21 | Antonio Gibson (GTD) | Wsh vs NYG |
| 22 | Cordarrelle Patterson | Atl @ NO |
| 23 | Jamaal Williams | Det @ NYJ |
| 24 | D'Andre Swift | Det @ NYJ |
| 25 | D'Onta Foreman | Car vs Pit |
| 26 | Jerick McKinnon | KC @ Hou |
| 27 | Leonard Fournette | TB vs Cin |
| 28 | A.J. Dillon | GB vs LAR |
| 29 | Cam Akers | LAR @ GB |
| 30 | Michael Carter | NYJ vs Det |
| 31 | Chuba Hubbard | Car vs Pit |
| 32 | Rex Burkhead (GTD) | Hou vs KC |
| 33 | Samaje Perine | Cin @ TB |
| 34 | Dare Ogunbowale | Hou vs KC |
| 35 | Marlon Mack | Den vs Ari |
| 36 | Kyren Williams | LAR @ GB |
| 37 | Tyler Allgeier | Atl @ NO |
| 38 | Jaylen Warren | Pit @ Car |
| 39 | Kenneth Gainwell | Phi @ Chi |
| 40 | Joshua Kelley | LAC vs Ten |
