All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:50 AM ET.
| Rank | Player | Match |
| 1 | Austin Ekeler | LAC @ Ari |
| 2 | Tyreek Hill | Mia vs Hou |
| 3 | Davante Adams | LV @ Sea |
| 4 | Derrick Henry | Ten vs Cin |
| 5 | Christian McCaffrey | SF vs NO |
| 6 | Travis Kelce | KC vs LAR |
| 7 | Josh Jacobs (GTD) | LV @ Sea |
| 8 | Kenneth Walker III | Sea vs LV |
| 9 | Jonathan Taylor (GTD) | Ind vs Pit |
| 10 | DeAndre Hopkins | Ari vs LAC |
| 11 | Travis Etienne | Jax vs Bal |
| 12 | A.J. Brown | Phi vs GB |
| 13 | Tee Higgins | Cin @ Ten |
| 14 | Jaylen Waddle | Mia vs Hou |
| 15 | Nick Chubb | Cle vs TB |
| 16 | Jeff Wilson Jr. | Mia vs Hou |
| 17 | Alvin Kamara | NO @ SF |
| 18 | Mark Andrews (GTD) | Bal @ Jax |
| 19 | James Conner | Ari vs LAC |
| 20 | Aaron Jones | GB @ Phi |
| 21 | Tyler Lockett | Sea vs LV |
| 22 | Deebo Samuel | SF vs NO |
| 23 | Najee Harris | Pit @ Ind |
| 24 | Rachaad White | TB @ Cle |
| 25 | Dameon Pierce (GTD) | Hou @ Mia |
| 26 | D.K. Metcalf | Sea vs LV |
| 27 | David Montgomery | Chi @ NYJ |
| 28 | Keenan Allen | LAC @ Ari |
| 29 | Mike Evans | TB @ Cle |
| 30 | Samaje Perine | Cin @ Ten |
| 31 | Miles Sanders | Phi vs GB |
| 32 | Latavius Murray | Den @ Car |
| 33 | Antonio Gibson | Wsh vs Atl |
| 34 | Terry McLaurin | Wsh vs Atl |
| 35 | Chris Godwin | TB @ Cle |
| Rank | Player | Match |
| 36 | Christian Kirk | Jax vs Bal |
| 37 | Amari Cooper | Cle vs TB |
| 38 | Michael Pittman Jr. | Ind vs Pit |
| 39 | DeVonta Smith | Phi vs GB |
| 40 | Courtland Sutton | Den @ Car |
| 41 | Michael Carter | NYJ vs Chi |
| 42 | Chris Olave | NO @ SF |
| 43 | Tyler Boyd | Cin @ Ten |
| 44 | Isiah Pacheco | KC vs LAR |
| 45 | Josh Palmer | LAC @ Ari |
| 46 | Garrett Wilson | NYJ vs Chi |
| 47 | Brandon Aiyuk | SF vs NO |
| 48 | George Pickens | Pit @ Ind |
| 49 | Allen Lazard | GB @ Phi |
| 50 | Diontae Johnson | Pit @ Ind |
| 51 | Pat Freiermuth | Pit @ Ind |
| 52 | D.J. Moore | Car vs Den |
| 53 | Cordarrelle Patterson | Atl @ Wsh |
| 54 | Curtis Samuel | Wsh vs Atl |
| 55 | JuJu Smith-Schuster | KC vs LAR |
| 56 | George Kittle | SF vs NO |
| 57 | D'Onta Foreman | Car vs Den |
| 58 | Christian Watson | GB @ Phi |
| 59 | Parris Campbell | Ind vs Pit |
| 60 | Marquise Brown (GTD) | Ari vs LAC |
| 61 | Brian Robinson | Wsh vs Atl |
| 62 | Brandin Cooks (GTD) | Hou @ Mia |
| 63 | James Robinson | NYJ vs Chi |
| 64 | Mack Hollins | LV @ Sea |
| 65 | Donovan Peoples-Jones | Cle vs TB |
| 66 | Drake London | Atl @ Wsh |
| 67 | Zay Jones | Jax vs Bal |
| 68 | Tyler Higbee (GTD) | LAR @ KC |
| 69 | Treylon Burks | Ten vs Cin |
| 70 | Corey Davis | NYJ vs Chi |
