All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:39 AM ET.
| Rank | Player | Match |
| 1 | Derrick Henry | Ten @ Hou |
| 2 | Cooper Kupp | LAR vs SF |
| 3 | Justin Jefferson | Min vs Ari |
| 4 | Tyreek Hill | Mia @ Det |
| 5 | Saquon Barkley | NYG @ Sea |
| 6 | Stefon Diggs | Buf vs GB |
| 7 | Davante Adams (GTD) | LV @ NO |
| 8 | Christian McCaffrey | SF @ LAR |
| 9 | Josh Jacobs | LV @ NO |
| 10 | Alvin Kamara | NO vs LV |
| 11 | Jonathan Taylor | Ind vs Wsh |
| 12 | Tony Pollard | Dal vs Chi |
| 13 | Joe Mixon | Cin @ Cle |
| 14 | DeAndre Hopkins | Ari @ Min |
| 15 | Nick Chubb | Cle vs Cin |
| 16 | Kenneth Walker III | Sea vs NYG |
| 17 | Dameon Pierce | Hou vs Ten |
| 18 | Dalvin Cook | Min vs Ari |
| 19 | CeeDee Lamb | Dal vs Chi |
| 20 | Jaylen Waddle | Mia @ Det |
| 21 | Rhamondre Stevenson | NE @ NYJ |
| 22 | A.J. Brown | Phi vs Pit |
| 23 | Tee Higgins | Cin @ Cle |
| 24 | Amon-Ra St. Brown (GTD) | Det vs Mia |
| 25 | Aaron Jones | GB @ Buf |
| 26 | D'Andre Swift | Det vs Mia |
| 27 | Chris Olave | NO vs LV |
| 28 | Tyler Lockett (GTD) | Sea vs NYG |
| 29 | Raheem Mostert | Mia @ Det |
| 30 | Miles Sanders | Phi vs Pit |
| 31 | D.J. Moore | Car @ Atl |
| 32 | Eno Benjamin | Ari @ Min |
| 33 | D'Onta Foreman | Car @ Atl |
| 34 | Tyler Boyd | Cin @ Cle |
| 35 | DeVonta Smith | Phi vs Pit |
| Rank | Player | Match |
| 36 | Brandin Cooks (GTD) | Hou vs Ten |
| 37 | Brandon Aiyuk | SF @ LAR |
| 38 | Gabriel Davis | Buf vs GB |
| 39 | Amari Cooper | Cle vs Cin |
| 40 | Adam Thielen | Min vs Ari |
| 41 | Najee Harris | Pit @ Phi |
| 42 | Devin Singletary | Buf vs GB |
| 43 | Michael Pittman Jr. | Ind vs Wsh |
| 44 | Michael Carter | NYJ vs NE |
| 45 | David Montgomery | Chi @ Dal |
| 46 | George Kittle | SF @ LAR |
| 47 | Darrell Henderson | LAR vs SF |
| 48 | Terry McLaurin | Wsh @ Ind |
| 49 | Diontae Johnson | Pit @ Phi |
| 50 | Jakobi Meyers | NE @ NYJ |
| 51 | Dallas Goedert | Phi vs Pit |
| 52 | Curtis Samuel | Wsh @ Ind |
| 53 | T.J. Hockenson | Det vs Mia |
| 54 | Wan'Dale Robinson | NYG @ Sea |
| 55 | Tyler Allgeier | Atl vs Car |
| 56 | Garrett Wilson | NYJ vs NE |
| 57 | Brian Robinson | Wsh @ Ind |
| 58 | Darren Waller (GTD) | LV @ NO |
| 59 | Drake London | Atl vs Car |
| 60 | Kareem Hunt | Cle vs Cin |
| 61 | Robert Woods | Ten @ Hou |
| 62 | Zach Ertz | Ari @ Min |
| 63 | Tyler Higbee | LAR vs SF |
| 64 | Hunter Renfrow | LV @ NO |
| 65 | Romeo Doubs | GB @ Buf |
| 66 | Chase Claypool | Pit @ Phi |
| 67 | George Pickens | Pit @ Phi |
| 68 | Jamaal Williams | Det vs Mia |
| 69 | Josh Reynolds | Det vs Mia |
| 70 | Donovan Peoples-Jones | Cle vs Cin |
