All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:49 AM ET.
| Rank | Player | Match |
| 1 | Austin Ekeler | LAC vs Sea |
| 2 | Derrick Henry | Ten vs Ind |
| 3 | Saquon Barkley | NYG @ Jax |
| 4 | Davante Adams | LV vs Hou |
| 5 | Josh Jacobs | LV vs Hou |
| 6 | Ja'Marr Chase | Cin vs Atl |
| 7 | Tyreek Hill | Mia vs Pit |
| 8 | Leonard Fournette | TB @ Car |
| 9 | Joe Mixon | Cin vs Atl |
| 10 | Jonathan Taylor | Ind @ Ten |
| 11 | CeeDee Lamb | Dal vs Det |
| 12 | Deebo Samuel | SF vs KC |
| 13 | Travis Kelce | KC @ SF |
| 14 | Mark Andrews (Q) | Bal vs Cle |
| 15 | Kenneth Walker III | Sea @ LAC |
| 16 | Nick Chubb | Cle @ Bal |
| 17 | Mike Williams | LAC vs Sea |
| 18 | Breece Hall | NYJ @ Den |
| 19 | Amon-Ra St. Brown | Det @ Dal |
| 20 | Jaylen Waddle (GTD) | Mia vs Pit |
| 21 | Dameon Pierce | Hou @ LV |
| 22 | Tee Higgins | Cin vs Atl |
| 23 | Aaron Jones | GB @ Wsh |
| 24 | D.K. Metcalf | Sea @ LAC |
| 25 | Mike Evans | TB @ Car |
| 26 | Rhamondre Stevenson | NE vs Chi |
| 27 | Ezekiel Elliott | Dal vs Det |
| 28 | D'Andre Swift (GTD) | Det @ Dal |
| 29 | Michael Pittman Jr. | Ind @ Ten |
| 30 | David Montgomery | Chi @ NE |
| 31 | Raheem Mostert | Mia vs Pit |
| 32 | Amari Cooper | Cle @ Bal |
| 33 | Chris Godwin | TB @ Car |
| 34 | Jakobi Meyers | NE vs Chi |
| 35 | Allen Lazard | GB @ Wsh |
| Rank | Player | Match |
| 36 | Najee Harris | Pit @ Mia |
| 37 | Courtland Sutton | Den vs NYJ |
| 38 | Brandin Cooks | Hou @ LV |
| 39 | Christian Kirk | Jax vs NYG |
| 40 | Diontae Johnson | Pit @ Mia |
| 41 | Travis Etienne | Jax vs NYG |
| 42 | Tyler Lockett (GTD) | Sea @ LAC |
| 43 | Brandon Aiyuk | SF vs KC |
| 44 | Robert Woods | Ten vs Ind |
| 45 | Terry McLaurin | Wsh vs GB |
| 46 | Tony Pollard | Dal vs Det |
| 47 | JuJu Smith-Schuster | KC @ SF |
| 48 | Drake London | Atl @ Cin |
| 49 | Michael Gallup | Dal vs Det |
| 50 | A.J. Dillon | GB @ Wsh |
| 51 | Clyde Edwards-Helaire | KC @ SF |
| 52 | George Kittle | SF vs KC |
| 53 | Curtis Samuel | Wsh vs GB |
| 54 | Keenan Allen (GTD) | LAC vs Sea |
| 55 | Gerald Everett | LAC vs Sea |
| 56 | Tyler Boyd | Cin vs Atl |
| 57 | Jerry Jeudy | Den vs NYJ |
| 58 | Jamaal Williams | Det @ Dal |
| 59 | James Robinson | Jax vs NYG |
| 60 | D.J. Moore | Car vs TB |
| 61 | Brian Robinson | Wsh vs GB |
| 62 | Romeo Doubs | GB @ Wsh |
| 63 | Kareem Hunt | Cle @ Bal |
| 64 | T.J. Hockenson | Det @ Dal |
| 65 | Rashod Bateman (GTD) | Bal vs Cle |
| 66 | Alec Pierce | Ind @ Ten |
| 67 | Christian McCaffrey | SF vs KC |
| 68 | Chase Claypool | Pit @ Mia |
| 69 | Kyle Pitts | Atl @ Cin |
| 70 | George Pickens | Pit @ Mia |
