All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:48 AM ET.
| Rank | Player | Match |
| 1 | Austin Ekeler | LAC vs Sea |
| 2 | Derrick Henry | Ten vs Ind |
| 3 | Saquon Barkley | NYG @ Jax |
| 4 | Josh Jacobs | LV vs Hou |
| 5 | Leonard Fournette | TB @ Car |
| 6 | Joe Mixon | Cin vs Atl |
| 7 | Jonathan Taylor | Ind @ Ten |
| 8 | Kenneth Walker III | Sea @ LAC |
| 9 | Nick Chubb | Cle @ Bal |
| 10 | Breece Hall | NYJ @ Den |
| 11 | Dameon Pierce | Hou @ LV |
| 12 | Aaron Jones | GB @ Wsh |
| 13 | Rhamondre Stevenson | NE vs Chi |
| 14 | Ezekiel Elliott | Dal vs Det |
| 15 | D'Andre Swift (GTD) | Det @ Dal |
| 16 | David Montgomery | Chi @ NE |
| 17 | Raheem Mostert | Mia vs Pit |
| 18 | Najee Harris | Pit @ Mia |
| 19 | Travis Etienne | Jax vs NYG |
| 20 | Tony Pollard | Dal vs Det |
| Rank | Player | Match |
| 21 | A.J. Dillon | GB @ Wsh |
| 22 | Clyde Edwards-Helaire | KC @ SF |
| 23 | Jamaal Williams | Det @ Dal |
| 24 | James Robinson | Jax vs NYG |
| 25 | Brian Robinson | Wsh vs GB |
| 26 | Kareem Hunt | Cle @ Bal |
| 27 | Christian McCaffrey | SF vs KC |
| 28 | Tyler Allgeier | Atl @ Cin |
| 29 | Jeff Wilson | SF vs KC |
| 30 | Kenyan Drake | Bal vs Cle |
| 31 | Caleb Huntley | Atl @ Cin |
| 32 | Melvin Gordon | Den vs NYJ |
| 33 | Antonio Gibson | Wsh vs GB |
| 34 | Damien Harris (Q) | NE vs Chi |
| 35 | Latavius Murray | Den vs NYJ |
| 36 | D'Onta Foreman | Car vs TB |
| 37 | Rex Burkhead | Hou @ LV |
| 38 | Michael Carter | NYJ @ Den |
| 39 | Dontrell Hilliard | Ten vs Ind |
| 40 | Rachaad White | TB @ Car |
