All position ranks are: QB RB WR TE FLEX DEF
These rankings were updated as of Sun 9:28 AM ET.
| Rank | Player | Match |
| 1 | Jonathan Taylor | Ind vs Ten |
| 2 | Saquon Barkley | NYG vs Chi |
| 3 | Christian McCaffrey (GTD) | Car vs Ari |
| 4 | Austin Ekeler | LAC @ Hou |
| 5 | Nick Chubb | Cle @ Atl |
| 6 | Leonard Fournette | TB vs KC |
| 7 | Derrick Henry | Ten @ Ind |
| 8 | Khalil Herbert | Chi @ NYG |
| 9 | Aaron Jones | GB vs NE |
| 10 | Cordarrelle Patterson (GTD) | Atl vs Cle |
| 11 | Jamaal Williams | Det vs Sea |
| 12 | Najee Harris | Pit vs NYJ |
| 13 | Javonte Williams | Den @ LV |
| 14 | Josh Jacobs | LV vs Den |
| 15 | James Conner | Ari @ Car |
| 16 | Jeff Wilson | SF vs LAR |
| 17 | Antonio Gibson | Wsh @ Dal |
| 18 | James Robinson | Jax @ Phi |
| 19 | Ezekiel Elliott | Dal vs Wsh |
| 20 | Dameon Pierce | Hou vs LAC |
| Rank | Player | Match |
| 21 | A.J. Dillon | GB vs NE |
| 22 | Miles Sanders | Phi vs Jax |
| 23 | Kareem Hunt | Cle @ Atl |
| 24 | Rashaad Penny | Sea @ Det |
| 25 | Clyde Edwards-Helaire | KC @ TB |
| 26 | Breece Hall | NYJ @ Pit |
| 27 | Tony Pollard | Dal vs Wsh |
| 28 | Devin Singletary | Buf @ Bal |
| 29 | Michael Carter | NYJ @ Pit |
| 30 | Rhamondre Stevenson | NE @ GB |
| 31 | Damien Harris | NE @ GB |
| 32 | Melvin Gordon | Den @ LV |
| 33 | J.K. Dobbins | Bal vs Buf |
| 34 | Travis Etienne | Jax @ Phi |
| 35 | Cam Akers | LAR @ SF |
| 36 | Darrell Henderson | LAR @ SF |
| 37 | Nyheim Hines | Ind vs Ten |
| 38 | Rex Burkhead | Hou vs LAC |
| 39 | J.D. McKissic | Wsh @ Dal |
| 40 | Jerick McKinnon | KC @ TB |
